1. FUNDAMENTAL MICROBIOLOGY INTRODUCTION John Sippel, Ph.D.

2. FUNDAMENTAL MICROBIOLOGY SYLLABUS Course Meetings Course Description Texts Course Learning Outcomes General Class Policies General Lab Policies Dates Grading Missed Exams Academic Integrity

3. FUNDAMENTAL MICROBIOLOGY COURSE OUTLINE Immunology Microbiology Infectious Disease Microbial Diseases by Systems

4. FUNDAMENTAL MICROBIOLOGY COURSE OUTLINE Immunology –Elements of the immune response Cells of the Immune System Cytokines, Chemokines, Complement, Eicosanoids Apoptosis, Acute Phase Response Inflammation, Fever –Innate Immunity 1 st Line = Barriers: mechanical, chemical 2 nd Line = inflam, complement, phagocytosis, interferon –Adaptive Immunity Humoral = antibody Cell Mediated = cytotoxic T cells, activated Macs

5. FUNDAMENTAL MICROBIOLOGY COURSE OUTLINE Microbiology Bacteriology structure, physiology Gram pos, Gram neg, Mycobacteria, Spirochetes Virology structure / replication; icosohedral / helical RNA / DNA; nominclature Mycology yeasts / molds dermatophytes, subcutaneous, systemic, opportunist Parasitology protozoa: amoeba, sporozoa, flagellates helminths: nematodes, trematodes, cestodeds

6. FUNDAMENTAL MICROBIOLOGY COURSE OUTLINE Infectious Diseases –Epidemiology; reservoirs Emerging infectious diseases Bioterrorism –Route of entry –Pathogenesis –Host response –Diagnosis –Management Antibiotics –Prevention Chemoprophylaxis immunoprophylaxis

7. FUNDAMENTAL MICROBIOLOGY COURSE OUTLINE Microbial Diseases by Systems –Respiratory –Digestive –Genitourinary –Central Nervous System (CNS) –Blood –Skin, eyes –HIV and AIDS