1. Erik Joling Some examples from the project ‘Microscale experiments’ U NIVERSITEIT VAN A MSTERDAM Faculty of Science

2. 24 May 2000MicroQuim 20002 Prime Directive of Microscale Chemistry Thou shalt not demonstrate

3. 24 May 2000MicroQuim 20003 Glassware

4. 24 May 2000MicroQuim 20004 Low-cost heating device

5. 24 May 2000MicroQuim 20005 Chlorophyll from green leaves methanol green leaves

6. 24 May 2000MicroQuim 20006 Experiments must… …be performed during a forty-five minute period …fit into the curriculum …replace the macroscale experiments in the textbook …open new perspectives

7. 24 May 2000MicroQuim 20007 Column chromatography aluminium oxide mixture of potassium permanganate and potassium dichromate 0.5M nitric acid 1M sulfuric acid

8. 24 May 2000MicroQuim 20008 Synthesis of indigo 0.1 g 2-nitrobenzaldehyde 0.3 ml acetone 0.4 ml water 2 ml 1M sodium hydroxide 2 ml ethanol 0.1 g sodium dithionite

9. 24 May 2000MicroQuim 20009 Indigo STS-topic: age-old natural dye first synthetic dye production by Hoechst and the decline of the Indian indigo culture

10. 24 May 2000MicroQuim 200010 Sublimation of benzoic acid benzoic acid activated carbon crunched ice

11. 24 May 2000MicroQuim 200011 Esterification acetic acid + 1-butanol = 1-butyl acetate + water One reaction, three experiments: use of a catalyst determination of equilibrium constant upset the equilibrium

12. 24 May 2000MicroQuim 200012 Contact me micro@chem.uva.nl www.chem.uva.nl/chemeduc/microschaal …/MicroQuim2000