1. Key For All Figures CYAN NODE = DBF ORANGE = PRO BROWN = Gov’t YELLOW = Pharma GRAY = VC WHITE = Other Triangle = New Entrant Circle = Incumbent Node size = standardized network degree, constant within figures RED TIE= R&D GREEN = FINANCE BLUE = COMMERCIAL.. MAGENTA = LICENSING Figure 4a. 1988 Main Component, All Ties Figure 4b. 1989 Main Component, New Ties

2. Fig 5a. 1992 All Ties Fig 5b. 1993 New Ties

3. Figure 6a. 1995 All Ties Figure 6b. 1996 New Ties

4. Figure 7a. 1997 All Ties Figure 7b. 1998 New Ties