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Oral cavity Esophagus Stomach Small intestine Large intestine Rectum Liver Gallbladder Pancreas Ingestion Digestion Absorption Compaction Defecation
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Palatine tonsils Lingual tonsils Uvula Taste: CN VII & IX Motor to tongue: CN XII Mouth – mechanical breakdown & chemical digestion Stratified squamous epithelium
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Intrinsic salivary glands in tongue, lips & cheeks secrete saliva 98% water amylase - starch lipase - fats mucus – binds & lubricates lysozyme - bacteria Extrinsic salivary glands parotid gland submandibular gland sublingual gland parotid submandibular sublingual Salivary glands
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Esophagus stratified squamous epithelium skeletal – mixed – smooth esophageal hiatus – T7 gastrointestinal reflux Diaphragm Lower esophageal sphincter
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Constriction spots: where aorta arches over where left bronchus crosses over where it passes through diaphragm Barium swallow
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Mucosa: epithelium, CT, smooth mm, nodules Submucosa: CT, BV, nerves glands, nodules Muscularis externa inner circular outer longitudinal oblique (stomach only) Serosa (visceral peritoneum) Layers of the digestive tract
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Parasympathetic: vagus & S2-4 Sympathetic Enteric nervous system symp postganglionic fibers parasymp ganglia parasym postganglionic fibers Innervation of the gut
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spleen Kidney & adrenal gland Transverse colon Stomach
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Fundus Body Pylorus Pyloric sphincter smooth mm Rugae Stomach anatomy Greater curvature Lesser curvature
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Gastric pit cardiac & pyloric glands gastric glands mucous cell (c & p) = mucus parietal cell (g) = HCl, intrinsic factor chief cell (g) = pepsinogen, lipase enteroendocrine cell (all) = gastrin stem cell (all) Peptic ulcers bacteria, aspirin, NSAID smoking Tagamet, antibiotics mucosa submucosa Muscularis externa (Long., circular, oblique) Visceral peritoneum Muscularis mucosa Stomach histology
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Small intestine duodenum jejunum ileum Chemical digestion Absorption
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Relationship of duodenum to pancreas and gallbladder gallbladder = stores bile (emulsifies fats) Pancreas = bicarb & enzymes
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Circular folds (variable) Peyer’s patches
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Villi absorptive cells microvilli goblet cells largest in duodenum Intestinal crypts goblet cells stem cells Paneth cells (lysozyme) enteroendocrine cells Duodenal glands submucosa alkaline mucus Peyer Patches lymph nodules lacteal lymph capillary chyle (fatty lymph) Microscopic anatomy of the small intestine
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Gastric bypass Distal bypass (RGB) Most common
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Ileocecal junction Ileocecal valve Cecum appendix Teniae coli – muscularis externa Haustra – pouches Epiploic appendages - fatty peritoneal pouches
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Ascending colon Right colic (hepatic) flexure rectum Left colic (splenic) flexure Absorbs water & salt Eliminates feces Anatomy of the colon
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Ileocecal valve Appendix Rectum Anal canal Sigmoid colon Epiploic appendages Tenia coli Haustrum
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rectum Rectal valve Anal canal External anal Sphincter (skeletal mm) Internal anal Sphincter (smooth mm) Anal sinuses Hemorrhoidal veins Levator ani Anatomy of the anal canal
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Abdominopelvic cavity Lined with peritoneum visceral parietal
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Mesentery: double layer of parietal peritoneum that suspends digestive organs from abdominal wall provides passageway for blood, nerves & lymph Intraperitoneal Retroperitoneal
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Intraperitoneal Retroperitoneal
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Lesser omentum: extends from stomach to liver Greater omentum: extends from greater curvature of stomach
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Branches of the abdominal aorta
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Stomach & intestines sup. & inf. mesenteric veins Hepatic portal vein Liver sinusoids Hepatic veins Inferior vena cava Hepatic portal system – 70% of blood
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