1. AGIL Active Glucose/InsuLin Control System Design Team: Daniel Hewlett Michael Wires Concept: Provide diabetics with continuous blood glucose monitoring and insulin delivery in a single device, controlled wirelessly through a PocketPC interface.

2. Background: Diabetes Glucose (Sugar) is where the body gets energy. Insulin controls the amount of sugar in the bloodstream. Insulin allows the body’s cells to absorb glucose, lowering glucose levels in the blood. Diabetes: The body cannot control glucose levels correctly, often because it cannot produce insulin. So, diabetics are dependant on various methods of: Blood glucose monitoring Blood glucose monitoring Insulin delivery Insulin delivery Today, these two tasks must be done separately.

3. Our Solution AGIL combines the best methods (according to studies) of: blood glucose monitoring: Continuous glucose monitoring blood glucose monitoring: Continuous glucose monitoring insulin delivery: Insulin pump insulin delivery: Insulin pumpMotivation: By consulting with users, we found that the tasks they want to perform divide sharply into two categories: quick, efficient, very common tasks, and quite infrequent, but useful, tasks. Features: Blood glucose levels constantly and immediately visible Blood glucose levels constantly and immediately visible Stylus-Free operation (one finger) Stylus-Free operation (one finger) Automatic behind-the-scenes record-keeping Automatic behind-the-scenes record-keeping Visualization of data through color charts and graphs Visualization of data through color charts and graphs Communication for emergencies and regular consultation Communication for emergencies and regular consultation

4. Required Components Insulin Pump A programmable device that can deliver insulin continuously and in discrete doses. The insulin pump used in the AGIL system features: Wireless Communication to PocketPC Wireless Communication to PocketPC Integrated Continuous Glucose Monitoring Integrated Continuous Glucose MonitoringPocketPC.NET Compact Framework.NET Compact Framework Wireless Communications Wireless Communications InternetInternet PhonePhone Sound and Vibration Sound and Vibration Status Pod Status Pod

5. Demo

6. Usability Study Number of Subjects: 8 Age Range: 14 to 82 (Average: 44.75) Reported PocketPC skills range: 1-5 (out of 7) Included both Type 1 and Type 2 diabetics Users performed 5 tasks using AGIL on a PocketPC device, including: Setup Setup Eat a meal Eat a meal Change schedule Change schedule Send a graph Send a graph Respond to a notification Respond to a notification

7. Study Results

8. Conclusions and Future Work Lessons Learned Final Design Final Design Users made few errors and found operation simple and efficientUsers made few errors and found operation simple and efficient Received well by target users, more than earlier designsReceived well by target users, more than earlier designs Future Work Large Scale Large Scale Longitudinal study w/ fully-functional system, to determine effectiveness and identify further needsLongitudinal study w/ fully-functional system, to determine effectiveness and identify further needs Medium Scale Medium Scale Explore and evaluate other visualizations and direct manipulation techniquesExplore and evaluate other visualizations and direct manipulation techniques Small Scale Small Scale Finish implementation – including customizationFinish implementation – including customization

9. Questions?