1. Bio 328 Human Heredity Professor Debbi Morrissette dmorriss@csusm.edu Office Hours: Mon/Wed 9:15-9:45am Location: Sci2 Room 141

2. Course Objectives Gain fundamental understanding of how genetic information is passed from one generation to subsequent generations. We will explore how genetic information varies and how this variability underlies human traits, heritable diseases and evolution of our species. Required Text Human Genetics: Concepts and Applications, 7th or 8th Edition. Ricki Lewis, McGraw-Hill

3. Index Card Instructions Name Name Nickname Nickname Class (freshman, junior, etc) Class (freshman, junior, etc) Major Major Hobbies/Interests Hobbies/Interests Future Plans Future Plans Why Human Heredity? Why Human Heredity?

4. Grading Attendance and Class Participation 21pts 7% Quizzes25pts (5pts each) 8% Homework assignments44pts (2pts each) 15% Writing assignment50pts 17% 4 Exams160pts (40pts each) 53% TOTAL300pts 100 %

5. Attendance: is mandatory. Students should read assigned chapters prior to class. There will be no make-ups for missed classes or quizzes. Quizzes: will be given at the instructor’s discretion and in one of a variety of formats (in-class written questions, take-home questions, etc). Homework: will be assigned at the end of each lecture and will consist of 5-10 short answer questions covering that day’s lecture material. Homework will be due at the start of the following lecture period. Writing assignment: students will be assigned a heritable disease topic to research and write a brief report on. Exams: are not cumulative. We will have a “potluck review session” on the last day of class to help you prepare for the final (which is also not cumulative). Make-up exams will be given only in extreme cases with appropriate documentation (i.e. doctor’s note).

6. Late Policy Assignments turned in late will be reduced by one full letter grade for each day late (e.g. a “B+” paper turned in 2 days late becomes a “D+” paper ~ouch!~) Academic Dishonesty Cheating of any kind will not be tolerated Cheating of any kind will not be tolerated. Any student caught cheating will receive a zero on the assignment and risks failing the course. If you are having difficulty understanding the material, come and see me during office hours, schedule an appointment, or contact me via e-mail and I will do my best to help you. Students with Special Needs If you have a verified special need, please see me ASAP so that we can contact the Disabled Student Services office (located in Craven Hall 5205 at Ext. 4905) and ensure that you are accommodated.

7. What is Heredity? Heredity Heredity the passage of characteristics from one generation to the next the passage of characteristics from one generation to the next Genes Genes the units of heredity the units of heredity composed of the long molecule deoxyribonucleic acid ( DNA) composed of the long molecule deoxyribonucleic acid ( DNA) contain the “recipes” for proteins contain the “recipes” for proteins Genetics Genetics the study of inherited traits and their variation the study of inherited traits and their variation Genome Genome all of the DNA from an organism all of the DNA from an organism

8. Levels of Genetics 1. DNA 2. Gene 5. Individual 3. Chromosome 4. Genome 7. Population 6. Family

9. Applications of Genetics Establishing identity and ancestry Establishing identity and ancestry Forensics Forensics Health care Health care Predictive medicine Predictive medicine Animal models Animal models Agriculture Agriculture Genetically modified foods Genetically modified foods Ecology Ecology Metagenomics (all DNA in a habitat) Metagenomics (all DNA in a habitat)