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Cell Membranes Separating Dead from Alive
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Identify the radical below. 1.Amine 2.Hydroxyl 3.Carboxyl 4.Monosaccharide
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Identify the molecule shown. 1.Butene 2.Propene 3.Propane 4.Butane 5.None of the above are a good response.
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What is the function of the molecule shown below? 1.Energy storage 2.Component of cell membrane 3.Fuel source 4.Regulatory
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I. Functions Living part of the cell-legitimate cell organelle Separates living from the nonliving world Semipermeable-regulates what enters and exits the cell Partitions the cell into different regions where different functions take place Participates in chemical reactions Transmits signals between outside of cell and the cytoplasm[
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II.Cell membrane characteristics A.Semipermeable B.Elastic C.Wettable D. Very thin-around 10 um
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II.Early model A.Davison Danielli Model 1. mainly lipid 2. aqueous channels 3. surface protein 4. weaknesses
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Phospholipids interacting in water- amphipathic
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RBC cell membrane-clearly resembles Davson-Danielli model
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III. Fluid mosaic model A.Main ingredients Phospholipids Proteins both intrinsic and extrinsic Cholesterol Glycocalyx
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Your textbook’s Diagram
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B. Protein functions
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What do you think the function of this membrane protein might be? 1.Transport 2.Cell to cell adhesion 3.Cell to cell recognition 4.Energy production
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Electron micrograph of cell membrane http://www.med.uiuc.edu/histo/large/atlas/i mage/temgi3/75000a1.htmhttp://www.med.uiuc.edu/histo/large/atlas/i mage/temgi3/75000a1.htm
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C. Chemical properties of membrane 1. Lateral fluidity 2. Two dimensional fluidity-rapid movement of lipids and proteins 3. Flexible 4. Self sealing 5. Can fuse
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C. Chemical properties of membrane 6.Effect of saturated vs. unsaturated 7.Role of cholesterol
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IV. Function of Cell Membrane- Passive Transport A. Diffusion 1. definition 2. example 3. across cell membrane
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Your textbook’s figure of diffusion
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IV. Function of Cell Membrane- Passive Transport B. Facilitated Diffusion 1.mediated by intrinsic protein 2. diffusion gradient- no ATP 3. glucose entrance into cell 4. boy scout analogy
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C. Osmosis 1. Definition 2. U-tube 3.Explanation 4.Common examples 5. Terms of tonicity 6.Turgor pressure
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In which direction will water move? 1.A => B and B rises 2.B => A and A rises 3.A B and the sides stay at the same level 4.No idea
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Your textbook’s figure of osmosis
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Figur e 5- 13 Page 106 Plasma membrane Vacuole Vacuolar membrane (tonoplast) Cytoplasm Plasma membrane Vacuole Nucleus (a) (b)(c)
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V. Function of cell membrane-active transport A.Definition B.Endocytosis –1. Phagocytosis
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Phagocytic vesicles
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2. Pinocytosis Figur e 5- 19 Page 111 Microvilli Pinocytotic vesicle Cytosol
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3. Receptor mediated pinocytosis Figur e 5- 20b Page 112 0.25µm (b)
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C. Exocytosis
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D.Membrane Pumps 1.Materials are moved against concentration gradient 2.An integral protein molecule is involved 3.ATP is necessary 4.Sometimes membrane potentials are produced 5.Na ion-K ion pump is an example
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Figur e 5- 15b Page 108 ATP ADP 1. Three sodium ions bind to the transport protein 2. A phosphate group is transferred from ATP to the transport protein 3. The transport protein under- goes a conformational change, releasing three sodium ions outside the cell. 6. The transport protein returns to its original shape: Two potassium ions are released inside the cell 5. The phosphate is released 4. Two potassium ions bind to the transport protein (b)
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