1. NICLS: Development of Biomedical Computing and Information Technology Infrastructure Presented by Simon Sherman August 15, 2005

3. NICLS was established by the Nebraska Board of Regents in October, 2001 The Center has three member institutions: UNL, UNMC, and UNO. CU is an academic partner of the Center Presently, more 44 faculty members from the three UN campuses and CU are participating in the work of NICLS

4. Mission Statement F acilitate interdisciplinary (Mathematics, Computer Science, Information Technology, Molecular Biology, Genetics, Biochemistry, Pharmaceutical Science, etc.) collaboration among Nebraska's scientists P rovide Nebraska's researchers, educators, and students with efficient access to Bioinformatics tools and to a growing number of databases on biologically important molecules E nhance the competitiveness (and thus the ability to attract extramural funding) of ongoing and future research programs in Nebraska

5. Computing Infrastructure:

6. www.nicls.net

7. Computing Infrastructure:

8. Bioinformatics Educational and Training Laboratory at the Scott Technology Center, Omaha

9. Intel-based multiprocessor clusters at UNMC, UNL, UNO and CU were set up and maintained 1 Gb high-speed fiber-optic communication line between four campuses was laid The Computational Chemistry Facility and Bioinformatics Research Laboratory at UNO, as well as Bioinformatics Shared Resource at UNL and UNMC were established Examples of Infrastructure Development Activities:

10. Workshop, “DNA Microarray Analyses”, was organized Short course on Bioinformatics was organized Exhibitions and conferences, "Bioinformatics and Biomedical Computing in Nebraska" were organized in Omaha in 2003, 2004, and 2005 Annual Hawaii International Conference On System Sciences Advanced Computational Approaches and IT Techniques in Bioinformatics (Bioinformatics Minitrack of the Software Technology Track) has been organized in 2004 and 2005 Examples of Educational Activities:

14. INBRE Content Management and Information Sharing System (INBRE CMISS)

19. SOURCES OF EXTERNAL FUNDING: NIH: Cancer Center Support Grant; NIH COBRE: Nebraska Center for Viral Pathogenesis; NIH BRIN: Nebraska Training Network in Functional Genomics; NRI: Nebraska Research Initiative.

20. Future Directions Upgrade existing Bioinformatics Infrastructure by adding new clusters and data storage and by linking the clusters at UNMC, UNL, UNO and CU to form the Nebraska Biomedical Computer Grid Deploy and disseminate Bioinformatics approaches, LIMS and Content Management and Information Sharing Systems for the use in the Life Science Core Facilities and laboratories