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Pushing Brachytherapy one step Further Bryce Allred Dec. 6 th 2010
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Brachytherapy Methods
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Brachytherapy Isotopes 1910- urethral radium 1601 yr half life 1922- many complications Au-198 γ-ray of.412 MeV Half life of 2.7 days I-125 –.027 MeV γ rays – 60 day half life
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α/β Ratios - N*(α*D+β*D^2) S= e α is the linear term dealing with double strand break β Is the quadratic term dealing with single strand break
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New Isotopes Palladium-103 has proven to be very effective External beam therapy is currently compensating for lack of brachytherapy
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Electrons travel finite distance A photons probability of attenuation makes it unsafe Electrons can treat an organ without harming other organs
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Choosing Isotope Needs similarly even distribution Energy of around 5 MeV and a half life between 10 and 40 days
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Conclusion May prove to be very effective in isolating treatment. Computer simulations and phantom readings will be used to perform research
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