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DNA Replication DNA is replicated before cell division, when a cell divided into two cells
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Enzymes help DNA replication occur. –Helicase- unzips the two stands of DNA breaking the hydrogen bonds that hold them together. –DNA Polymerase adds complementary nucleotides A-T G-C –DNA Ligase connects fragments of DNA on the lagging stand to make a continuous molecules.
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Replication fork DNA polymerase New strand Original strand DNA polymerase Nitrogenous bases Replication fork Original strand New strand
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Proofreading After the two daughter strands are complete, other enzymes “proof read” the DNA checking the original or parent strand. DNA Polymerase makes about 1 mistakes in ever 500 base pairs, but after proofreading as few as 1 mistake in a billion base pairs can be found… Helping to prevent mutation from occurring!!
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