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MCMP 441 DOR 101 Pharmacology Abdelkader Ashour, Ph.D. 3 rd Lecture.

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Presentation on theme: "MCMP 441 DOR 101 Pharmacology Abdelkader Ashour, Ph.D. 3 rd Lecture."— Presentation transcript:

1 MCMP 441 DOR 101 Pharmacology Abdelkader Ashour, Ph.D. 3 rd Lecture

2 MCMP 441 Autonomic Nervous System

3 MCMP 407 Organization of The Nervous System Central Nervous System: Brain and spinal cord Peripheral Nervous System Somatic Nervous System Autonomic Nervous System SympatheticParasympathetic Efferent DivisionAfferent Division

4 MCMP 407 Efferent division of the peripheral nervous system

5 MCMP 407

6 Some anatomic and neurotransmitter features of autonomic and somatic motor nerves

7 MCMP 407 l Mimic or block the effects of the two primary neurotransmitters, Acetylcholine and Norepinephrine/Epinephrine l Drugs that mimic neurotransmitters are referred to as “receptor agonists” HThese drugs activate receptors l Drugs that block neurotransmitters are referred to as “receptor antagonists” HThese drugs block the endogenous neurotransmitters from activating receptors How do drugs influence the ANS?

8 MCMP 407 l Parasympathetic nervous system Mimic acetylcholine = cholinergic = muscarinic agonists = parasympathomimetic Block acetylcholine = anticholinergic = muscarinic antagonist = parasympatholytic l Sympathetic nervous system Mimic norepinephrine = adrenergic = adrenergic agonist = sympathomimetic Block norepinephrine = antiadrenergic = adrenergic antagonist = sympatholytic Classification of drugs affecting the ANS


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