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Lecture 3 BIO 344
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Hydrophobic amino acids in green and yellow
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Predicting transmembrane helices from the amino acid sequence
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Secondary structure of protein
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Examples of β-barrels
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Detergent Micelle in Water
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DVD clip 38
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Structures of Two Commonly Used Detergents
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Liposome for studying membrane properties
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Membrane Proteins in Human Red Blood Cells
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Most Membrane Proteins have Structural Functions
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Freeze Fracture Electron Microscopy
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Band 3 can be seen as intramembrane particles, more on P face than E face
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DVD clip 41
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Chapter 11 Membrane Transport of Small Molecules and the Electrical Properties of Membranes
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Molecule movement across lipid bilayer without proteins
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Permeability across lipid bilayer
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Carrier Proteins
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Channel Proteins
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Passive vs. Active Transport
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Three Ways of Driving Active Transport
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Electrochemical gradient vs. membrane potential Can work additively or against each other
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Three Ways of Driving Active Transport
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Conformational Change in Carrier Protein mediates passive transport
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Three Types of Carrier Mediated Transport
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DVD Clip 43
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Mechanism of Na + - glucose carrier Binding of Na + and glucose is cooperative
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DVD Clip 44
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Microvilli in the small intestine
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Transcellular transport of glucose
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