1. The Origins of Neuropsychology Psychology - Experimental Neurology – Clinical Emergent Clinical Fields: Behavioral Neurology Neuropsychology Emergent Experimental Fields: Cognitive Neuroscience Experimental Neuropsychology

2. Research Populations Human patients with brain damage or disorders Neurologically intact humans Nonhuman animals primates rodents invertebrates

3. Patients with Brain Damage The lesion approach Examples: 1. HM remember him??? 2. Blindsight huh? Any problems with this approach???????

4. WHAT'S NEW WITH THE AMNESIC PATIENT H.M.? Suzanne Corkin H.M. became amnesic in 1953. Since that time, nearly 100 investigators, first at the Montreal Neurological Institute and since 1966 at the Massachusetts Institute of Technology, have participated in studying him. We all understand the rare opportunity we have had to work with him, and we are grateful for his dedication to research. He has taught us a great deal about the cognitive and neural organization of memory. We are in his debt.

6. Problems with the Lesion Approach Variability in regions of damage Example: language mapping

7. BTW: DISCLAIMER The broken brain may not process information in the same way as the intact brain….. EG: Stiles – developmental studies of spatial processing

8. Behavioral Methods Clinical Interviews Information from caretakers Neuropsychological Testing –Battery Approach –Decision Tree Approach Experimental Testing

14. Physiological Methods CAT – Computerized Axial Tomography MRI – Magnetic Resonance Imaging FMRI PET Electrophysiological Recording –EEG –ERP –Depth Electrodes

19. GOOD BYE