1. structure of Aggrecan aggregate

2. Collagen fibril embedded in proteoglycan molecules

4. Fibroblast surrounded by collagen fibrils

5. Collagen fibrils in tadpole skin This arrangement is also found in bone and the cornea

6. Elastic fibers in a dog’s aorta

7. Each elastin protein in the network can expand and contract as a coil

8. Fibronectin is an extracellular protein that helps cells attach to the matrix

9. Connective tissue underlying the epithelium contains a variety of cells and extracellular matrix components

10. A model of the basal lamina

11. basal lamina in the cornea of a chick’s embryo

13. Cross Section of Kidney

14. Filtration is one step in urine formation

15. Structure of Nephrons

16. Inside Bowman’s Capsule

19. Basal Lamina plays an important role in filtration

21. extracellular matrix can propagate order within a tissue

24. Proteases bound to surface receptors are needed to crawl through basal lamina

25. Melanoma cells with low filamin levels crawl poorly and tend not to metastasize

27. Integrin is a transmembrane heterodimer

28. Cells can regulate the activity of their integrins

29. Focal Adhesion Kinase deficient fibroblasts have more focal adhesions and can not spread

30. Matrix dependent cell survival in embryonic development

31. Signaling Pathways in Cancer