1. Finding Funding in Medical Research Professor Peter Ratcliffe Nuffield Department of Medicine

2. What makes a good scientist? Believer Scholar Caution Thought Delinquent Leadership Non-Believer Action

3. Laboratory or Field? Small or Big? New or Established?

4. The Research Field New Knowledge New Knowledge New Opportunity New Technology Ideally Both Ideally Both Tractability (nothing else matters) Tractability (nothing else matters)

5. A Personal Story Epo Oxygen Epo gene identified Tissue culture model established

6. Getting Funded Write clearly for the general scientific readership

7. Writing an application (1)  Create an outline  Discuss widely - colleagues at all levels - experts in the field - experts in the field  Read the regulations

8. Writing an application (2)  Formal language  Least adjectives  Least abbreviations  Logical progression  Description proportional to difficulty ‘After doing a degree in science, I PCR-cloned an entirely novel gene in MAPK signalling’

9. Writing an application (3) MANAGING RISK  Do not obscure, be honest  Give options  Be reasonable about extent of ‘downstream’ work and support requested  Be reasonable about timescale  Do not add experiments just because they are feasible  Maintain focus

10. Writing an application (4) YOU MUST ANSWER ALL 3 QUESTIONS Why this topic? Why me? Why my institution?