1. Apnea Response System University of Hartford Senior Design Project M. Shalane Regan Diane Eager Michael Porter 4/10/2007

2. Apnea Greek word for “without breath” The stop of respiration for approximately 10-20 seconds 30% to 50% of all premature infants 90% of those that are under 28 weeks of gestation have apnea.

3. Apnea (continued) Central apnea (apnea prematurity) Obstructive apnea Mixed Apnea

4. Current Treatment Stimulation from nurse/ Dr/ parent when breathing stops Continuous Monitoring Disadvantages: –Too big in size –Many false positives –Disruptive

5. Current Hospital Monitor Pulse Ox EKG Thoracic Impedance Nasal Air Flow

6. Apnea Event in an Infant http://www.empiricaltechnologies.com/page19.html

7. Methods Gantt Chart Functional Decomposition Quality Function Deployment Morphological Chart Failure Mode and Effect Analysis of Design (DFMEA)

8. Preferences and Customer Requirements Parent –Safety –Dependability –Easy of use Doctor –Size –Dependability –Few to no false positives Nurse –Portable –Compatible with current computers –Rotating screen

9. Quality Function Deployment

10. QFD (continued) Program Capabilities –Operating system –Baseline settings Battery Life –Long life –Alarm

11. QFD (continued)

12. Sensors –EKG, Thoracic Impedance –Size –Alarm Display on Monitor –Easy to use –Digital –Legible

13. Morphological Chart

14. Current Design Wireless system Wireless patient box Three electrodes Vibration stimulator wired to patient box Station box Computer reads signals and determines whether infant needs vibration stimulation

15. Circuit Board Top Layer PCB Bottom Layer PCB

16. Upon Completion Working prototype Different alarms for... –Apnea event –Elevated Heart Rate –Low battery –Disconnect alarm Automated stimulation Continuous monitoring and recording of heart rate, oxygen saturation, thoracic impedance, and number of episodes

17. Future Design Completely wireless System Eliminate electrodes using cell phone technology Keep manufacturing costs to a minimum Replacement parts can be sold in local stores Wireless battery technology Adjustable components for each individual

18. Questions ?