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The versatility of catabolism
Plasma membrane
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Fermentation enables cell to produce ATP w/o O2
aerobic anaerobic *Fermentation generates ATP by substrate-level phosphorylation
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Cellular Respiration: one more time!
SUMMARY: Organic + Oxygen Carbon + Water + Energy Compounds Dioxide C6H12O6 + 6 O CO2 + 6 H2O + energy Redox reactions release energy *Redox reactions *loss of an electron = oxidation *gain of an electron = reduction C6H12O6 + 6 O CO2 + 6 H2O oxidation reduction
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*Dehydrogenases *Nicotinamide adenine dinucleotide *ATP can be synthesized in one of two ways: Substrate-level phosphorylation Oxidative phosphorylation
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Cellular Respiration: an overview
3 metabolic stages: *glycolysis *Krebs cycle *electron transport chain
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Glycolysis harvests chemical energy by oxidizing glucose to pyruvate
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The Krebs cycle: energy-yielding oxidation
cytosol mitochondrial matrix per pyruvate per glucose 1 ATP 2 ATP 4 NADH 8 NADH 1 FADH2 2 FADH2
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Electron transport and ATP synthesis
FADH2 Some more accounting: *For every NADH that transfers e- to ETC, 3 H+ are pumped across the inner mt membrane *For every FADH2, 2 H+ are pumped across the inner mt membrane
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Fermentation enables cell to produce ATP w/o O2
aerobic anaerobic *Fermentation generates ATP by substrate-level phosphorylation
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