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Eduard Strasburger Walther Flemming Meiosis & Mitosis
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I.
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Animation 3.2
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Animation 3.3
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II.
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Genes exist, come in pairs Gametes – only 1 gene copy pair of copies SEGREGATE alleles combine randomly In offspring Each gamete – only 1 gene copy START A / a
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a+ / a Genes exist, come in pairs Gametes – only 1 gene copy pair of copies SEGREGATE What about second law?
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Animation 5.1a
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Mendel’s 2 nd Law: Genes segregate independently אין תלות בין גנים בסגרגציה (הפרדה)
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Recombinant Parental Parental
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R/r Y/y If we have a third gene for seed size –big>small: B/b, and TRI-hybrids ¾ of these seeds will be big ¼ of these seeds will be small ¾ of these seeds will be big ¼ of these seeds will be small ¾ of these seeds will be big ¼ of these seeds will be small ¾ of these seeds will be big ¼ of these seeds will be small 27/64 9/64 3/64 9/64 3/64 1/64 64/64 93319331
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YY Yy yy If we look at the GENOTYPE ratios - With a second gene for seed texture – round/wrinkled: 1/4 of these seeds will be RR 2/4 of these seeds will be Rr 1/4 of these seeds will be rr 1/4 of these seeds will be RR 2/4 of these seeds will be Rr 1/4 of these seeds will be rr 1/4 of these seeds will be RR 2/4 of these seeds will be Rr 1/4 of these seeds will be rr 1/16 2/16 1/16 2/16 4/16 2/16 1/16 2/16 1/16 16/16 Genotype ratios: 1:2:1:2:4:2:1:2:1 Phenotype ratios: 9:3:3:1
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Mendel’s rules are relevant for organisms that sexually reproduce: diploid/haploid –Plants, Animals, many Monera… Those that ‘do’ meiosis
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Sex chromosomes: The breakthrough to the chromosomal theory of inheritance III-IV
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Nettie Stevens Thomas H. Morgan
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Animation 3.3
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Thomas H. Morgan
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Board Reciprocal White Red Mothers Fathers Red White Daughters Sons
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習字 書道
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המופיליה F6 F7
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אחיות כנשאיות – לא חולות
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To be a male: Fly: ratio of X chromosomes to autosomes = 1 Man: Presence of Y chromosome
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Barr body For ‘dosage compensation’, 1 X chromosome is condensed, silenced in females
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Y? Y linked trait??
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First Second (reciprocal)
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Mammals Fruitflies Moths Homogametic Heterogametic Heterogametic Homogametic
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