1. Cutaneous Manifestation of Cardiovascular Disease Done by Mohammad Binhussein

2. Dermatologists may be the first physician to diagnose an underlying cardiovascular disease

3. skin findings in addition to general dermatologic signs suggestive of cardiovascular disease 1.Infective endocarditis 2.Acute rheumatic fever 3.Cholesterol embolization syndrome 4.Lipid disorders 5.Kawasaki disease 6.Pseudoxanthoma elasticum

4. Infective endocarditis Osler nodes

5. Infective endocarditis Janeway lesions

6. Risk Factor? heart valves degenerative valve disease prosthetic valves intravenous drug use recent cardiac or dental surgery mitral valve prolapse and rheumatic heart disease

7. Causative Organism? Usually caused by viridans streptococci & staphylococci

8. postinfectious sequela of a group A β-hemolytic streptococcal pharyngitis Acute rheumatic fever

9. Erythema marginatum

10. Cholesterol embolization syndrome Livedo reticularis

11. Describe? red or blue, mottled, netlike discoloration

12. Xanthelasma Lipid Disorder

13. soft yellow macules or plaques Describe?

14. Premature development may indicate familial hypercholesterolemia

15. Pseudoxanthoma elasticum

16. genetic disorder of connective tissue affecting the skin, eyes, and cardiovascular

17. plucked chicken skin

18. Kawasaki

19. immune-mediated vasculitis mucocutaneous lymph node syndrome fever lasting 5 or more days without explanation combined with at least 4 of the 5 principal clinical features, as follows: (1) bilateral conjunctival injection, (2) oral mucous membrane changes, (3) peripheral extremity changes, (4) polymorphous rash, and (5) cervical lymphadenopathy

20. LEOPARD syndrome

21. The lentigines are dark brown irregularly shaped macules ranging in size from pinpoint to 5 cm with involvement of the face, neck, and upper trunk

22. Cardiocutaneous lentiginosis syndrome and multiple lentigines syndrome, is an autosomal dominant disorder of variable penetrance stands for Lentigines, ECG changes, Ocular telorism, Pulmonary valve stenosis, Abnormal genitalia, Retardation of growth, and Deafness.