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Lecture 4 BIO 344 Chapter 10 and 11.

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Presentation on theme: "Lecture 4 BIO 344 Chapter 10 and 11."— Presentation transcript:

1 Lecture 4 BIO 344 Chapter 10 and 11

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4 Membrane Transport of Small Molecules and the Electrical Properties of Membranes
Chapter 11

5 Molecule movement across lipid bilayer without proteins

6 Permeability across lipid bilayer

7 Carrier Proteins

8 Channel Proteins

9 Passive vs. Active Transport

10 Three Ways of Driving Active Transport

11 Electrochemical gradient vs. membrane potential
Can work additively or against each other

12 Three Ways of Driving Active Transport

13 Conformational Change in Carrier Protein mediates passive transport

14 Three Types of Carrier Mediated Transport

15 DVD Clip 43

16 Mechanism of Na+ - glucose carrier Binding of Na+ and glucose is cooperative

17 DVD Clip 44

18 Microvilli in the small intestine

19 Transcellular transport of glucose

20 The Na+ - K+ pump is an ATPase

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22 DVD clip 42

23 Response of red blood cells to changes in osmolarity of extra cellular fluids

24 Distribution of phospholipids and glycolipids in the lipid bilayer of human red blood cells

25 Few Ions are required to cause a large change in membrane potential

26 Electrochemical gradient vs. membrane potential
Can work additively or against each other

27 Selectivity of a K+ channel

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29 DVD Clip 45

30 Ion Channels fluctuate between closed and open conformations

31 Gating of K+ channel

32 Gating of Ion Channels

33 A Typical Vertebrate Neuron

34 Ball and Chain Model of Rapid inactivation of ion channel

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36 Propagation of Action Potential

37 Changes in Na+ channels and the action potential

38 Changes in Na+ channels and the action potential

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