1. Mitosis & Chromosomes Histology SSN September 22, 2004 Presented By: Tresha Edwards & Nadia Goodwin

2. The Cell Cycle What is the ploidy of the cell at stage G2? Cell during Interphase

3. STAGES OF MITOSIS Whitefish Mitosis Key Structures: Nuclear Membrane, Chromosomes, Spindles, Cytoplasmic membrane I PM A T

4. Prophase Assembly of mitotic spindle Chromosome condensation

5. Prophase

6. Prometaphase Nuclear envelope breakdown Attachment of chromosomes to spindle apparatus

7. Metaphase Alignment of the chromosomes at the metaphase plate Rate-limiting step of mitosis! Metaphase plate Kinetochore microtubules Spindle poles

8. Anaphase Anaphase A Sister chromatids separate and move towards poles Kinetochore microtubules shorten Anaphase B Spindle poles move apart Cytokinesis begins

9. Telophase Nuclear envelope reassembly Chromosome decondensation Cytokinesis is completed

10. Question 1 Put the numbered cells in sequential order. 2 1 3 4 5

11. Question 2 This structure could be part of the a)Kinetochore b)Centromere c)Microtubule Organizing Center (MTOC) d)Cleavage furrow e)Chromatid

12. Question 3 What characteristics would you expect to find in the cell at the pointer: I. Spindle apparatus II. Nuclear envelope III. Contractile ring IV. Equatorial plate a)I and II only b)I, II, and IV c)I and IV d)All

13. Question 4 1 All of the following pertain to the cell labeled 1, EXCEPT: a)Nuclear envelope has disbursed b)Mitotic spindle has begun formation c)Centrosomes have separated d)DNA has been duplicated