1. IMMUNOLOGY PURSUIT 2 General Immunology Specific Response Non Specific Response HIVDefinitions and Acronyms F0 G0 H0 I0 J0

2. QUESTION What is the best means of preventing infection?

3. ANSWER Hand washing

4. QUESTION What is the name of the chemical that can cause a puncture in the cell membrane?

5. ANSWER Perforin

6. QUESTION :What is another name for Type II immunity?

7. ANSWER ACQUIRED

8. QUESTION What cells are involved in the Humoral response?

9. ANSWER B CELLS

10. QUESTION What are the three cells that are found in the acquired immune system?

11. ANSWER B cells, T cells, and Dendritic Cells

12. QUESTION What are naïve T cells?

13. ANSWER T cells that have not been differentiated into either helper T cells or cytotoxic T cells.

14. BONUS QUESTION If you answer the question correctly, you will receive a free turn whenever you would like.

15. BONUS QUESTION In what locations in the body are lymphocytes made immunocompetent?

16. BONUS ANSWER Thymus and Bone Marrow

17. QUESTION At what point in a person’s life are T cells immunocompetent?

18. Answer At birth

19. QUESTION What lineage gives rise to B and T cells?

20. ANSWER Lymphoid

21. QUESTION Virally infected cells are attacked by which of the CD cells (a number is needed)?

22. ANSWER CD 8

23. QUESTION ANSWER

25. QUESTION What is the difference in location between monocytes and macrophages?

26. ANSWER Macrophages are found inside tissues and monocytes are found circulating throughout the blood stream

27. QUESTION Where is lysozyme found?

28. ANSWER In tears

29. QUESTION What is the function of the mucosal-ciliary escalator system?

30. ANSWER To trap foreign particles in the mucus and through the activity of the cilia to move the pathogens up from the respiratory area to the mouth.

31. QUESTION What ‘system’ is made up of chemicals that function similar to a series of dominos that can begin activity without the use of antibodies? Be very specific.

32. ANSWER Alternative Complement system

33. QUESTION After foreign proteins are broken down into peptides a piece of the peptide is moved toward the surface of the cell to serve as an antigen. What is this process of the antigen being ‘shown’ on the surface of the cell called?

34. ANSWER Presented

35. QUESTION In what parts of the world are the newest epidemics of HIV showing up? Name 3.

36. ANSWER China, Russia, Indonesia, New Guinea, Viet Nam, Baltic States

37. QUESTION Why do opportunistic infections begin to show up in HIV?

38. ANSWER Because helper T cells are no longer able to produce enough clones to offset the new virions being produced.

39. QUESTION When did AIDS first appear in the US?

40. ANSWER 1981/1982

41. QUESTION In the US, what racial/ethnic group is contracting HIV at the greatest rate?

42. ANSWER African Americans

43. QUESTION What are the three main categories of drug treatment for HIV?

44. ANSWER Protease Inhibitors, Nucleosides, Non- nucleosides.

45. QUESTION NK

46. ANSWER Natural killer cells

47. QUESTION Immunocompromised

48. ANSWER The immune system has been damaged and can no longer mount a defense against pathogens

49. QUESTION Index case

50. ANSWER The case/person which is considered the primary source of a disease.

51. QUESTION APC

52. ANSWER Antigen Presenting Cell

53. QUESTION Q: IL- (followed by a number)

54. ANSWER Interleukins