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2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 26 June 2015 9:18 PM.

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Presentation on theme: "2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 26 June 2015 9:18 PM."— Presentation transcript:

1 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 26 June 2015 9:18 PM

2 Pentazocine Opioid analgesic  receptor partial agonist or antagonist

3 Pentobarbital Sedative/Hypnotic Barbiturate

4 Pentostatin Antineoplastic Miscellaneous Enzyme inhibitor (blocks purine synthesis)

5 Perindopril Antihypertensive Converting enzyme inhibitor

6 Phencyclidine (PCP) Drug of abuse Hallucinogen

7 Phenobarbital Sedative/Hypnotic Anticonvulsant Barbiturate

8 Phenoxybenzamine Sympatholytic  adrenergic antagonist Antihypertensive

9 Phentolamine Sympatholytic  adrenergic antagonist Antihypertensive

10 Phenylephrine Sympathomimetic  1 adrenergic agonist Vasoconstrictor Nasal decongestant

11 Phenylpropanolamine Indirect sympathomimetic Nasal decongestant Removed from market* (may be in medicine cabinets!)

12 Phenytoin Anticonvulsant Class I antiarrhythmic Na + channel blocker (inactivated channels)

13 Physostigmine Anticholinesterase Bradycardic Vasodilator Bronchoconstrictor

14 Phytonadione Vitamin K Warfarin antagonist

15 Pilocarpine Cholinomimetic Muscarinic agonist Antiglaucoma Bronchoconstrictor

16 Pindolol Sympatholytic  adrenergic antagonist Antihypertensive Bronchoconstrictor

17 Pioglitazone Oral hypoglycemic Thiazolidinedione Insulin sensitizer

18 Pipecuronium Paralytic Paralyze skeletal muscles

19 Piperacillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking

20 Pirbuterol Sympathomimetic  2 adrenergic agonist Bronchodilator

21 Piroxicam NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

22 Platelet Activating Factor (PAF) Inflammatory mediator Lipid Hypotensive

23 Polyethylene glycol - electolyte solution Antidote Cathartic

24 Polymyxin B Antibiotic Disrupts gram negative cell membrane Binds phosphatidylethanolamine Bactericidal

25 Pralidoxime Antidote Cholinesterase reactivator

26 Pramipexole Antiparkinson Dopamine agonist (non-ergot)

27 Pravastatin Antihyperlipidemic HMG-CoA reductase inhibitor

28 Prazosin Sympatholytic  1 adrenergic antagonist Antihypertensive

29 Praziquantel Antihelminthic Treatment of trematode (fluke) and cestode (tapeworm) infections

30 Prednisone Adrenocorticosteroid Glucocorticoid Antineoplastic Anti-inflammatory Not by inhalation

31 Primaquine Antimalarial Eliminates hepatic forms of plasmodium

32 Primidone Anticonvulsant

33 Probenecid Uricosuric Adjunct in penicillin therapy

34 Probucol Antihyperlipidemic LDL oxidation inhibitor

35 Procainamide Class I antiarrhythmic Na + channel blocker (activated channels)

36 Procaine Local anaesthetic

37 Procaine Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Repository preparation Inhibits peptidoglycan cross-linking

38 Procarbazine Antineoplastic Miscellaneous Probably acts as alkylating agent

39 Prochlorperazine Antiemetic D 2 receptor antagonist Phenothiazine

40 Progesterone Progestin Natural female progestin

41 Proguanil Antimalarial Inhibits plasmodial dihydrofolate reductase

42 Prolactin Anterior pituitary hormone Regulator of lactation

43 Promethazine Classical antihistamine Antipsychotic Antiemetic H 1 antagonist

44 Propafenone Class I antiarrhythmic Na + channel blocker Weak  -blocker

45 Propofol General anaesthetic Intravenous anaesthetic

46 Propranolol Sympatholytic  adrenergic antagonist Class II antiarrhythmic Antihypertensive Bronchoconstrictor

47 Propylthiouracil Antithyroid Prevents synthesis of thyroid hormones (blocks iodine organification)

48 Prostaglandin D 2 (PGD 2 ) Bronchoconstrictor Cyclooxygenase product of arachidonate metabolism

49 Prostaglandin E 2 (PGE 2 ) Dinoprostone (Dinoprost) Oxytocic prostaglandin Inflammatory mediator Cyclooxygenase product of arachidonate metabolism Uterine stimulant Cervical ripener

50 Prostaglandin F 2 (PGF 2 ) Inflammatory mediator Cyclooxygenase product of arachidonate metabolism

51 Prostaglandin I 2 (PGI 2 ) Inflammatory mediator Inhibits platelet aggregation Cyclooxygenase product of arachidonate metabolism Prostacyclin

52 Protamine Sulfate Heparin antagonist

53 Pseudoephedrine Sympathomimetic  and  adrenergic agonist Vasoconstrictor Nasal decongestant

54 Psyllium hydrophilic mucilloid Bulk laxative

55 Pyrantel Pamoate Antihelminthic Treatment of intestinal roundworms

56 Pyrazinamide Antibiotic Major drug for tuberculosis

57 Pyridostigmine Anticholinesterase Vasodilator Treatment for myaesthenia gravis Bronchoconstrictor

58 Pyrimethamine Antimalarial Protein and nucleic acid synthesis inhibitor Plasmodial dihydrofolate reductase inhibitor

59 Quinapril Antihypertensive Converting enzyme inhibitor

60 Quinethazone Thiazide-like diuretic Na-Cl symporter inhibitor

61 Quinidine Antimalarial Protein and nucleic acid synthesis inhibitor Class I antiarrhythmic Intercalates in DNA Binds to ferriprotoporphyrin Na + channel blocker

62 Quinine Antimalarial Intercalates in DNA Binds to ferriprotoporphyrin

63 Quinopristin/Dalfopristin Streptogramin antibiotic Protein synthesis inhibitor 50S ribosomal subunit

64 Rabeprazole Antiulcer H + /K + ATPase inhibitor

65 Radioactive Iodide ( 131 I) Antithyroid Destruction of thyroid parenchyma

66 Raloxifene Antiestrogen Selective estrogen receptor modulator (SERM)

67 Ramipril Antihypertensive Converting enzyme inhibitor

68 Ranitidine Antihistamine Antiulcer H 2 receptor antagonist

69 Rebamipide Antiulcer

70 Repaglinide Oral hypoglycemic Meglitinide Insulinotropic

71 Reserpine Sympatholytic Antihypertensive

72 Resperidone Antipsychotic

73 Reteplase Thrombolytic Tissue plasminogen activator (tPA)

74 Ribavirin Antiviral Primarily used as aerosol for respiratory syncytial virus

75 Rifampin Antibiotic Nucleic acid synthesis inhibitor Inhibits DNA dependent RNA polymerase Major drug for TB

76 Rimantadine Antiviral Inhibits replication at the stage of uncoating Treatment of Influenza A

77 Ritodrine Sympathomimetic  2 adrenergic agonist Tocolytic Uterine relaxant

78 Ritonavir Antiretroviral Protease inhibitor (PI)

79 Rituxumab Antineoplastic Anti-CD20 antibody

80 Rocuronium Paralytic Paralyzes skeletal muscles

81 Rofecoxib NSAID Anti-inflammatory Cyclooxygenase 2 (COX-2) inhibitor

82 Ropinirole Antiparkinson Dopamine agonist (non-ergot)

83 Rosiglitazone Oral hypoglycemic Thiazolidinedione Insulin sensitizer

84 Salmeterol Sympathomimetic  2 adrenergic agonist Long acting bronchodilator

85 Saquinavir Antiretroviral Protease inhibitor (PI)

86 Saw palmetto Dietary supplement Treatment for benign prostatic hyperplasia (BPH)

87 Senna Contact cathartic Anthraquinone derivative

88 Scopolamine Anticholinergic Antiemetic Muscarinic receptor antagonist

89 Sertraline Antidepressant Selective serotonin reuptake inhibitor (SSRI)

90 Sildenafil Vasodilator Promotes erection

91 Silver sulfadiazine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical

92 Simethicone Anti-flatulent

93 Simvastatin Antihyperlipidemic HMG-CoA reductase inhibitor

94 Sirolimus Immunosuppressive Binds FKBP, inhibits mTOR (mammalian kinase target of rapamycin) & cell cycle progression Rapamycin

95 Sodium bicarbonate Antiulcer Antidote Antacid Alkalinization of urine to treat drug toxicity (esp. barbiturates, salicylates, methanol)

96 Sodium phosphate Saline (osmotic) cathartic

97 Sodium stibogluconate Tropical antiparasitic Organic antimonial Treatment of Leishmaniasis

98 Somatostatin Somatotropin Release-inhibiting Hormone (SRIH) Hypothalamic hormone Inhibits release of growth hormone from the anterior pituitary

99 Somatrem Growth hormone analogue Stimulates insulin-like growth factor I release (  growth at open epiphyses), lipolysis and skeletal muscle growth

100 Somatropin Growth hormone analogue Stimulates insulin-like growth factor I release (  growth at open epiphyses), lipolysis and skeletal muscle growth

101 Sotolol Class II antiarrythmic Sympatholytic  adrenergic antagonist


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