1. The Visible Human Project "The Visible Human Project includes digitized photographic images for cryosectioning, digital images derived from computerized tomography and digital magnetic resonance images of cadavers."

2. The Visible Human Project 1.Find a normal male and female cadaver 2.Fresh CT & MR 3.Fill blood vessels and cavities with contrast media 4.Pose and stabilize in opaque gel 5.Freeze the cadaver 6.Cut cadaver into blocks 7.Frozen CT 8.Grind down block and take photograph

3. Infuse blood vessels and fill cavities with contrast media (resin)

5. Cryo-section Data Collection

8. Data Collection

9. CT (bone)MRI (proton-density) MRI (T1)MRI (T2)

10. Data Collection

11. Photographic cross-sections: Volume Dimensions: 1760 x 1024 x 1878 Pixel Dimensions:.33 mm x.33 mm x 1 mm Pixel Depth: 24-bit (8-bits x RGB) Volume Size: 9.5 GB Computed Tomography (CT) - in fresh state: Volume Dimensions: 512 x 512 x 500 Pixel Dimensions: variable x variable x 1 mm Pixel Depth: 16-bit Volume Size: 250 MB Computed Tomography (CT) – in frozen state: Volume Dimensions: 512 x 512 x 1878 Pixel Dimensions: variable x variable x 1 mm Pixel Depth: 16-bit Volume Size: 939 MB Data Collection

12. Photographic cross-sections: Volume Dimensions: 1664 x 928 x 5189 Pixel Dimensions:.33 mm x.33 mm x.33 mm Pixel Depth: 24-bit (8-bits x RGB) Volume Size: 22.4 GB Computed Tomography (CT) - in fresh state: Volume Dimensions: 512 x 512 x 1730 Pixel Dimensions: variable x variable x 1 mm Pixel Depth: 16-bit Volume Size: 864 MB Data Collection

13. TransverseCoronalSagittal The Visible Human

14. Segmentation and Classification

15. Semi-automatic Segmentation Marr-Hildreth edge detection filter, seed filling and neighbor connectivity filter Spline interpolation of surface Mostly done by anatomists using a drawing and filtering program.

16. Segmentation

17. Classification

18. Classification

19. Classification