2. LYBRA: The Challenge 2.5 million people Life expectancy 4.5 years lower than UK average; ↑infant mortality; ↑drug abuse, smoking and binge drinking. NHS Workforce 55,000 medical, clinical and & managerial staff Spend circa £3.5 billion per year LYBRA partnership: Bradford & Airedale tPCT Bradford Teaching Hospitals NHSFT Leeds Partnerships NHSFT Leeds PCT Leeds Teaching Hospitals NHST University of Leeds University of York York Leeds Bradford

3. Why a LYBRA CLAHRC? We do things well We do them together We are an ambitious partnership Unparalleled opportunity

4. We do things well Bradford NHS Bradford Institute for Health Research 3 NIHR programmes: quality & safety, stroke, childhood obesity Leeds NHS £700k pa in HSR & trial income Translational research e.g. Leeds Musculoskeletal BMRU University of Leeds Institute of Health Sciences £21m HSR grants from SDO, HTA & national research councils University of York £36m HSR grants 2003-07 (£1m per WTE academic) Dept Health Sciences, CRD & Centre Health Economics

5. We Do Them Together

6. A Partnership With Ambition Core principles: High calibre HSR (& key performance indicators) Commissioning informed by research Distributed research settings Strong public engagement Tackling health inequalities Research capacity building within the NHS

7. LYBRA: An Unparalleled Opportunity Top Class HSR Service Development & Delivery Research-Led commissioning

8. LYBRA: step changes structures: new partnerships, themes supported by LYBRA partners ways of working: R&D embedded in frontline activities

9. Patient Involvement Truly committed Evidence:  involvement in existing R&D programmes  involvement in NHS and social services partners, e.g. Foundation Trust governors and members Using existing NHS structures Participation working group

10. Risks and Responses An NHS re-organization that changes the nature of the LYBRA partnership Strong, adaptable governance arrangements Creating novel networks Commitment of all LYBRA partners: LYBRA is a strategic investment Sustaining the networks in each theme Bottom-up thematic network development

11. Monitoring and Evaluation Output measures: embedded partnerships Outcome measures: key measures within each theme Cross-cutting TRIP-LAB theme

12. Governance

13. LYBRA Governance LYBRA Board: NHS Commissioner led Organisational commitment: Memorandum of Understanding Financial management Strong theme management Wider engagement –user/public – commissioners

14. Where do we end up? Here will be the “big ending” for Simon once raw materials from Justin are in…