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Computational Analysis of Transcript Identification Using GenBank
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Differentiation of hematopoietic cells
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Genome-wide gene expression
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SAGE (Serial Analysis of Gene Expression)
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SAGE & GLGI Overview
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SAGE tags match to many genes (Tags from Hashimoto S, et al. Blood 94:837, 1999)
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Tag Frequency Groups for 10-base Tag Set Containing 878,938 Tags for UniGene Human
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Unique Tags among 878,938 EST Derived Tags
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Unique Tags among 32,851 Gene Derived Tags
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Converting tag into longer 3’ sequence
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Generation of Longer 3'cDNA for Gene Identification (GLGI)
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UniGene Human 3’ Part Length Distribution
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Number of Tags which Move for k to k+25
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Unique Tags among 878,938 EST Derived Tags
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Unique Tags among 32,851 Gene Derived Tags
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Idealized Construction
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Random Model
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Ideal Case Tag Count Progression
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Myeloid Tag Matches with UniGene Human SAGE Tag Reference Database
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SAGE Tag Processing with GIST
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k-mer tree
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GIST Performance with Improved IO
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Conspirators Sanggyu Lee Janet D. Rowley San Ming Wang Terry Clark Andrew Huntwork Josef Jurek L. Ridgway Scott
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