1. SERONEGATIVE SPONDARTHRITIS
● Ankylosing spondylitis
● Psoriasis
● Reactive arthritis
● Reiters disease
● Ulcerative colitis
● Crohn’s disease
● (Whipple’s disease)

9. CHARACTERISTIC OF SERONEGATIVE SPONDARTHRITIDES
Absence of rheumatoid Familial clustering
factor Increased incidence
Involvement of sacro- of HLA-B27
iliac and spinal joints Common spectrum
Peripheral arthritis of extra-articular
(predominantly features (pre-
lower limb) dominantly muco-
Enthesopathy cutaneous)

10. PATTERNS OF PSORIATIC ARTHROPATHY
Distal interphalangeal joint disease with associated nail lesions.
Seronegative polyarthritis often variable and assymetrical, may develop transient ‘sausage digits’.
Deforming arthritis (‘arthritis mutilans’)
Spondylitis

11. FEATURES OF REITERS DISEASE
● Urethritis
● Conjunctivitis
● Arthritis
● Enthesopathy
● Sacroiliitis
● Keratoderma blenorrhagica
● Mouth ulcers
● Circinate balanitis
● Cervicitis
● Iritis

12. FEATURES OF WHIPPLE’S DISEASE
● Malabsorption
● Arthritis
● Fever
● Lymphadenopathy