1. Suffering from Osteoporosis? - Mathematical modeling of bone remodeling at cellular level Yanan Wang 31/10/2007

3. Osteoporosis

4.  How does osteoporosis relate to my work (bone remodeling)?

5. Bone remodeling cycle at cellular level

6. Bone remodeling (Coupling)

7. Significance of bone remodeling  Serving to adjust bone architecture.  Helping to repair microdamage.  Maintaing plasma calcium homeostastis.

8. Logical structure of the model

9. Reasons for including PTH  PTH is currently involved in clinical trials.  PTH 1-34 was recently approved by the Food and Drug Administration of America (FDA).

10. Intermittent vs Continuous

11. Biomechanical control of bone remodeling

12. Effect of electromagnetic field on remodeling

13. Conclusion

14. The end Thank you