1. Genetic exchange in bacteria/archaea OEB 192 – 10.09.20 (Worobey et al., 2010, last Friday)

2. Two “types” of HGT…

3. Comparison of HGT to “normal” sex

4. Detecting HGT: unlikely presence/absence HGT onlyLoss only (Koonin, 2003) Ex: glycerol-3-P DH

5. Detecting HGT: differential gene content (Welch et al., 2002)

6. Detecting HGT from genomes: atypical nt composition (Hacker & Carniel, 2001)

7. GC% bias across species (Lawrence & Ochman, 1997)

9. Wednesday (9/22): Limits to HGT

10. MSI Chalktalk Breakfast **Alternate Location: Haller Hall, Room 102, 1 st floor, 24 Oxford St ** Friday, Sept 24 th 8:45-9:30 am “Evolution of genes at the retrovirus-host interface” Welkin Johnson HMS Host: Cammie Lesser Please join us for coffee and pastries at 8:30 am - Directions to 24 Oxford St: http://www.msi.harvard.edu/ov_dir.htmlhttp://www.msi.harvard.edu/ov_dir.html - Join MSI-news listserv: Email: listserv@listserv.med.harvard.edu and in the body of your email, copy the text: subscribe msi-newslistserv@listserv.med.harvard.edu