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Enteric Nervous System gutgut Central Nervous System (CNS) brainbrain spinal cordspinal cord Peripheral Nervous System (PNS) cranial nerves (12 pr)cranial nerves (12 pr) spinal nerves (31 pr)spinal nerves (31 pr)
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CNS PNS
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sensory receptor sensory input integration motor input effector
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cell body dendrite Synapse axon Myelin sheath
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Schwann Cells Axon Nodes of Ranvier
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bipolar eye, ear, & olfactory unipolar multipolar most abundant type in CNS Dorsal root ganglion cells
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sensory receptors sensory neuron interneuron motor neuron effector
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Presynaptic neuron Postsynaptic membrane Ca 2+ Synaptic vesicles containing neurotransmitters
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Acetylcholine- slows heart rate; PNS Glutamate- most prevalent neurotransmitter in the brain Aspartate- in CNS GABA- inhibitory neurotransmitter Glycine- inhibitory neurotransmitter Norepinephrine- awakening from deep sleep Epinephrine- increase heart rate Dopamine- movement of skeletal muscles Seratonin- sensory perception, temp regulation, mood, sleep Nitric oxide- may play a role in memory and learning Enkephalin- inhibit pain impulses by suppressing release of substance P Substance P- enhances perception of pain tyrosine
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Converging circuit same source Pacinian corpuscles -- pressure different sources control of respiration Diverging Circuit permits broad distribution of a specific input types A. amplification B. divergence into multiple tracts
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Parallel after-charge circuit several neurons process same information at one time each chain has a different number of synapses, but eventually they all reconverge on a single output output neuron may go on firing for some time after input has ceased important in withdrawal reflexes longer-lasting output from small period of pain
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Reverberating Circuit axons extend back toward the sources of an impulse and further stimulate the presynaptic neuron helps maintain consciousness, muscular coordination, normal breathing, short term memory...
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synapses Efferent (motor) Afferent (sensory) Integration center
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Multiple Sclerosis Autoimmune disease Destruction of myelin sheath Scar tissue may form
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Epilepsy Rapid synchronous firing of neurons Seizure Treatments: Drugs Implants Brain surgery
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INQUIRY 1.What voltage is the threshold potential? 2.Describe depolarization, repolarization and hyperpolarization. 3.Which ion causes the neurotransmitters to be released across the synapse? 4.Name 2 instances that you can stimulate a neuron to depolarize. 5.What disease is characterized by myelin sheath degeneration? 6.Can all parts of the CNS regenerate if damaged?
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