1. Bacterial Infection of Bone By Dr. Humodi A. Saeed Associate Prof. of Medical Microbiology College of Medical Laboratory Science Sudan University of Science and Technology E mail address: Biotechsust@hotmail.com

2. Bacterial Infection of Bone

3. The Bone Definition

4. Bacterial Infection of Bone Origin of Bone Infections Microorganisms introduced during injury Microorganisms from the blood stream

5. Bacterial Infection of Bone Origin of Bone Infections Microorganisms introduced during operative procedures

6. Bacterial Infection of Bone Origin of Bone Infections Microorganisms from the blood stream

7. Bacterial Infection of Bone Actions of Microorganisms Localized in Bone Proliferate

8. Bacterial Infection of Bone Actions of Microorganisms Localized in Bone Produce cell death

9. Bacterial Infection of Bone Actions of Microorganisms Localized in Bone Spread within the bone shaft

10. Bacterial Infection of Bone Actions of Microorganisms Localized in Bone Incite a chronic inflammatory response with further destruction of bone

11. Bacterial Infection of Bone Actions of Microorganisms Localized in Bone

12. Types of Bacterial Infection of Bone 1.Osteomyelitis

13. Types of Bacterial Infection of Bone Types of Osteomyelitis 1.Hematogenous Osteomyelitis Originates with infectious organisms that reach the bone through the blood stream

14. Types of Bacterial Infection of Bone Types of Osteomyelitis 2.Contiguous Spread Osteomyelitis –Secondary to a contiguous focus of infection –Direct inoculation from an exogenous source or from an adjacent extraskeletal site

15. Types of Bacterial Infection of Bone Types of Osteomyelitis Chronic Osteomyelitis Occur secondary to an open wound

16. Bacterial Infection of Bone Prevention of Bone Infection 1.Careful cleaning and debridement of skeletal injuries

17. Prevention of Bone Infection 2.Strict operating room protocols

18. Thank you I would like to thank Dr. Neal R. Chamberlain