1. Study of Mid-Infrared Light Scattering Due to Skin for a Non-Invasive Glucose Monitor with an Automated Setup Kevin A. Bors, Sabbir Liakat, Anna P. M. Michel, and Claire F. Gmachl

2. Quantum Cascade Lasers –More efficient energy solutions –Field testing –Good for developing countries Mid-Infrared Technologies for Health and the Environment 2 MIRTHE and General Motivations for Research

3. Specific Motivation for Research Diabetes patients 3 Example absorption spectrum of glucose 1036 1080 1106 1152

4. Experimental Setup BARD (bi-axial rotation device) QCL (Quantum Cascade Laser) 4

5. Close-up of BARD setup 5 Experimental Setup

6. 6 Program Capabilities Variables Controlled by Program: Axis of rotation Range and precision of angular movements of that axis Position of other axis Range and Precision of Wavenumber Movements

7. Example scan using program 7 Results of an Automated Scan Measuring Reflected Light as a Function of Position Backscattered Light Intensity for Incidence φ=40°

8. Results of an Automated Scan Measuring Reflected Light as a Function of Position Light is Scattered by Dermis (Inner Layer of Skin) Glucose here proportional to level in blood Absorption Spectroscopy 8

9. Non-invasive glucose sensing Automation of BARD Independent work Thanks to PEI, MIRTHE, and Professor Gmachl’s Group 9 Summary, Future Work, and Acknowledgements