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PRPP synthetase Nucleoside phosphorylases Phosphoribosyl transferases
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The committed step of de novo purine nucleotide biosynthesis
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Phosphoribosylamine synthase: cooperativity with respect to PRPP concentration & product inhibition
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Outline of de novo purine nucleotide biosynthesis
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Outline of de novo pyrimidine nucleotide biosynthesis
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Enzymes I. Ribonucleotide reductase II. Nucleotide diphosphate kinase III. dCMP kinase IV. dUTP diphosphohydrolase V. dCMP deaminase VI. Thymidylate synthase VII. FH 2 reductase
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