1. Medical Chemistry An extraordinary subject Applied chemistry for MEDICAL STUDENTS

2. It spans from: –General Chemistry –Inorganic Chemistry –Analytical Chemistry –Organic Chemistry To: –Biochemistry –Physiology –Pharmacology

3. Organization of our curriculum General chemistry (physical chemistry) General chemistry (physical chemistry) (McMurray, Fay: Chemistry, 4th Edition; Darrel D. Ebbing: General Chemistry) All other similar texbooks can be used

4. Organic and bioorganic chemistry (P. Gergely: Organic and Bioorganic Chemistry For Medical Students, 3rd Edition) Analytical Chemistry: Practices and seminars only! seminars only! (G. Oszbach: Laboratory Experiments in Medical Chemistry, 1998)

5. Bioinorganic Chemistry: Obligatory subject (P. Gergely: Introduction to Bioinorganic Chemistry for Medical Students) Elective course (2 credits) (W. Kaim, B. Schwederski: Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life)

6. Laboratory Safety Chemistry laboratory can be a DANGEROUS PLACE to work in Eye safety: ALWAYS wear approved safety glasses or goggles

7. Further rules and regulations will be discussed on the first meeting with lab instructors: Group 1: Dr. Zoltán Berente Group 2: Dr. Veronika Nagy Group 3: Ms. Erika Turcsi Group 4: Dr. Veronika Nagy Group 5: Dr. Tamás Lóránd Group 6: Dr. Attila Agócs Group 7-8: Dr. László Márk

8. Intranet Medical Chemistry lectures and exam samples can be found at the following link: Medical Chemistry lectures and exam samples can be found at the following link: http://intranet.pote.hu/OKTATAS/biokemia /medical_chemistry.html

9. Chemistry The science that is concerned with the characterization, composition, and transformations of matter

10. Development of modern chemistry 1.Practical arts (-to 600 B.C.) Ancient Egypt and Mesopotamia –Production of metals from ores –Manufacture of Pottery –Brewing, baking –Preparation of medicines, drugs and dyes 2.Greek (600 B.C. to 300 B.C.) –Concept of four elements (earth, air, fire, water) –Atomic theory

11. 3.Alchemy (300 B.C. to 1650 A.D.) Alexandria, Arabs –Chemical apparatus, laboratory operations –Philosopher’s stone, elixir of life –Iatrochemistry (a branch of alchemy concerned with medicine) 4.Phlogiston (1650 to 1790) Combustion: wood + oxygen gas (from air) ashes + oxygen containing gases According to the phlogiston theory: wood ashes + phlogiston (removed by air) WOOD = ASHES + PHLOGISTON

12. 5.Modern Chemistry (1790- ) Antoine Lavoisier –Laws of chemistry –Modern terminology

13. Main branches of chemistry Analytical chemistry: separation, identification, and composition of materials composition of materials Organic chemistry: chemistry of the carbon compounds Inorganic chemistry: chemistry of the compounds other than carbon compounds Physical chemistry: study of the physical characteristics of materials and mechanisms of their reactions reactions Biochemistry: chemistry of living systems Nuclear chemistry: chemistry of subatomic particles and nuclear reactions