1. Chromatin Remodeling Review:

2. Crystal structure of a nucleosomal core particle

3. Race between transcription factors and histones: In vitro transcription and reconstituted chromatin:

4. Model of Transcriptional Activation

5. DNase Hypersensitive Regions

6. Histone post-translational modifications: *acetylation*deactylation

7. Activation and Repression:

8. Chromatin Immunoprecipitation:

9. Post-translational modifications: *phosphorylation *methlyation *others

10. Outcomes of Remodeling:

11. Remodeler Families:

12. Model of DNA Movement: