1. Questions of the Day:
What are the products of the reaction of phenyl magnesium bromide with
Formaldehyde
Acetone
Carbon dioxide
Benzoic acid?
(Write a reaction equation.)

2. Today: Conclusion of Grignard. TLC MiniQuiz
Next Tuesday, 3/17:
In LabLecture :
Your Questions. Introduction to Unknowns.
In Lab:
Midterm, 2:10 – 4pm, in your lab

3. Read questions carefully.
Midterm Exam (100 points) Tuesday, March 17, 2009, 14: :00 in your lab
Five problem sets.
Covers the material of labs and lab lectures during the first half of the semester (including Grignard/TLC). The exam will address chemical structures, reactions, mechanisms, procedures and reasons for them, calculations, problem sets, spectra related to our experiments, lab lecture material. See sample Midterm exam for style of problems.
Rules:
Cell phones off and in your pack.
Do bring a calculator, but not a "computer". No sharing ...
Do not leave the room during the exam.
No extra note paper; use back of pages if necessary.
Please no questions during exam (unless you discover a serious mistake). You can write: "if I understand the question this way ..."
No "late" exams... A midterm not taken earns the grade "F".
Start studying early.
Read questions carefully.
Proofread!

4. Grignard
Our multistep synthesis of triphenyl methanol, starting with the synthesis of our Grignard reagent:
Grignard Adduct

5. What is the purpose of adding dilute sulfuric acid to the adduct mixture?
Why do we add ligroin to the ether before evaporating to obtain our product?

6. What type of reactions are Grignard reactions?
How could you synthesize triphenyl methanol from a ketone, using our Grignard reagent?
b) How could you synthesize triphenyl methanol by a different method?

7. TLC Thin Layer Chromatography is an example of chromatography.
Other types of chromatography?
What is common to all types of chromatography?

8. TLC What is the moving phase, the stationary phase in our TLC?
Biphenyl
TLC
What is the moving phase, the stationary phase in our TLC?
What type of information do we expect from our TLC?

9. Introduction to Unknowns
Next time (3/17):
Your questions…
Introduction to Unknowns
In Lab:
Midterm, 2:10 – 4pm

10. (Write a reaction equation.)
MiniQuiz 6 Questions:
What are the products of the reaction of phenyl magnesium bromide, with
Acetone
Benzoic acid?
(Write a reaction equation.)