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APh161 - Lecture 2: The Rate of Things Rob Phillips California Institute of Technology (Pollard and Earnshaw)
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The Hierarchy of Time Scales
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E. Coli Cell Division: The Standard Stopwatch
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E. Coli Cell Division: The Bacterial Growth Curve http://www-micro.msb.le.ac.uk/LabWork/bact/-4L.jpg Other ways of counting cells 0.009/min
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The Eukaryotic Cell Cycle Pollard and Earnshaw Adapted from Murray and Hunt
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Cell Division Movies See CD accompanying Essential Cell Biology. There are beautiful movies of cell division.
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The Processes of the Central Dogma
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Timing of Gene Expression: How Cells Decide What to Eat Monod thesis
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Timing of Gene Expression Lucy Shapiro et al., Stanford
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Putting the Stopwatch on Cell Division and Cell Motility http://cmgm.stanford.edu/theriot/movies.htmhttp://cmgm.stanford.edu/theriot/movies.htm - the place to be! These movies allow for an estimate of the rate of actin polymerization. Show movies of cell division - problem often with the movies is no timer showing how long the video lasts in real time units. The concept is to estimate the rate of microtubule polymerization.
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A reminder on the cytoskeleton
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Embryonic Development: Telescoping up in Time
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