1. Chem. 133 – 1/27 Lecture

2. Introduction - Instructor: Roy Dixon Educational Background in Analytical Chemistry and Environmental Chemistry Most of my research currently is in HPLC technology/methodology development or applications

3. Learning Objectives of Class (Skills and Knowledge Set) Learn how instruments work Learn measures of instrument performance and what affects performance Know common applications of instruments (e.g. how can we use an instrument to determine a compound’s concentration, identity or structure) Connect instrument performance with method/sample/analyte demands

4. Roll Call and Adding Students Class normally has 12 students Currently 10 in class and ? on waitlist I will add 2 from waitlist and more if others drop I plan to add students by next Thursday Students wanting to add, but not currently on the waitlist will need to fill in my waitlist Possible class in Fall

5. Adding Students Priority for Adding Students 1.BS Chem majors graduating S’15 2.BS Chem majors graduating F’15 and BA Forensic majors graduating S’15 3.Any Chem/Biochem majors graduating by F’15 4.All others Within each category, preference given to those higher on waitlist You may be asked to show evidence for your graduation date

6. Handouts Syllabus Laboratory Schedule 1 st Homework Assignment

7. Syllabus Top 3 Items Lab Class room = Sequoia 516, but will spend time in ~6 other rooms too Office hours –can arrange meetings at other times Internet Site –will post handouts, keys to homework and exams, “practice” exams, Powerpoint lecture notes, and updates (e.g. see syllabus)

8. Syllabus Text Books –Harris (Quantitative Chemical Analysis) Main text We are using the 8 th Edition, older editions could be used but you must find the differences –Wayne (Chemical Instrumentation) For Electronics Avail at library reserve (if desired) + copies at main office –Rubinson and Rubinson (Contemporary Instrumental Analysis) For NMR instruction –Skoog et al. (Principles of Instrumental Analysis) Recommended for anyone interested in working as an analytical chemist

9. Grading Lecture Component Exams (44% of grade) –3 midterms (see syllabus for dates) –Comprehensive Final Exam (may be ACS multiple choice exam) Quizzes (8% of grade) –Roughly every 2 weeks unless near exam Homework (3% of grade) –Only a subset of problems will be turned in (Bold problems in first set)

10. Grading Lab Component Lab Reports/Lab Practical (35% of grade) –5 lab reports (one for each lab experiment) –Each report (or lab practical) worth 7% of total grade –Possibility to replace one lab report with a lab practical for selected experiments –Penalties for late labs (but 1 lab 1 period is acceptable in exchange for attending 1 Chem 294 seminar) –More on experiments in lab outline (will discuss in lab) Term Project (10% of grade) –Hand out to be given out soon –Will work on in lab during last 4 to 5 weeks, but basic due dates given earlier (e.g. topic, proposal, progress report) –A poster presentation is required

11. Topics Electronics –Emphasis on understanding multiple aspects of electronics for instruments –Some topics will be covered qualitatively Electrochemistry (fundamentals + qualitative understanding of ion selective electrodes) Spectroscopy –Fundamental sections (theory and spectrometer components) –Specific types (UV-Visible, fluorescence, atomic, and NMR) Mass Spectrometry Chromatography –Theory of separations, and main components –GC and HPLC

12. Homework Set 1 Three subsets (1.1, 1.2, and 1.3) Bold homework problems are graded; do not turn in other problems Subsets should be done before quizzes Solutions will be posted Data for 1 st problem not up yet Quizzes on days when homework is turned in (for sets 1.1 and 1.2)

13. Today’s Lecture Measures of Instrument Performance Overview of Electronics Electronic Definitions and Basic Laws

14. In Lab Today Data/Excel Basics –covering here Checking In First 15 pages of Lab Manual will be on website (if needed)

15. Measures of Instrument or Method Performance What is he talking about? Example: method accuracy Get class to come up with 7+ measures

16. Electronics Topics Covering –Basic DC Circuits (Ohm’s Law, Power Law, Kirchhoff’s Laws + applications) –Alternating Currents, Other Waveforms, and Fourier Transformation –RC Circuits –Diodes –Signal Digitization –Transducers –Operational Amplifiers (not covered quantitatively) –Noise

17. Electronics - Overview Generic Instrument Block Diagram Analog Electronics Transducer Analog Signal Processing Digital Electronics Analog to Digital Conversion Board Memory Signal Display Long-term Storage (Disk) Digital Signal Processing Exciter sample Digital to Analog (control)

18. Electronics From: David Zellmer, CSU Fresno http://zimmer.csufresno.edu/~davidz/Chem106/ModZoo/ModZoo.html Example Block Diagram for an Atomic Emission Spectrometer

19. Electronics Go to Board to Cover: Definitions, Ohm’s Law, Power Law and Kirchhoff’s Laws