1. ATTENDANCE FORM 8th NORTH WEST LIPID FORUM Wednesday 3 rd December 2014, 09:00-1600. To reserve your place, please complete the form and return at your earliest convenience to Lipid.Clinic@cmft.nhs.uk or Fax to 0161 276 4684Lipid.Clinic@cmft.nhs.uk CORRESPONDENCE DETAILS Name: ……………………………………………………………………………………………………………………... GP Surgery/Hospital:.…….…………………………………………………………………………………………. Role/Position:…………………………………………………………………………………………………………… Address: ………………………………………………………………………………………………………………….. ……………………………………………………………………………………………………………………………….. Postcode: ……………………………………………………………………………....................................... Contact Number: ……………………………………………………………………................................... Email Address: ………………………………………………………………………………………………………… Please state any dietary requirements: ……………………………………………………………………. Signature: ……………………………………………………………………………………………………………….. Date: …………………………………………………………………………………………………………………………

2. CPD accreditation 5 CPD applied for Invitation Organised by Dr Handrean Soran The organiser will not receive speaker honorarium or any other fee for chairing the sessions and organising the meeting This educational meeting has been supported by an unrestricted grant from Sanofi. Sanofi have had no input into the selection of speakers or topics for this meeting. 8 th NORTH WEST LIPID FORUM Wednesday 3 rd December 2014 8 th NORTH WEST LIPID FORUM Wednesday 3 rd December 2014 Venue: Radisson Blu Hotel, Manchester Airport, Chicago Avenue, Manchester Airport, Manchester M90 3RA, UK University of Manchester The Centre for Endocrinology & Diabetes

3. 08.50-0915Registration and Tea 09.15-0920Welcome Dr Handrean Soran Session 1Chair TBC 09.20-10.00NICE guidelines, their development and the international context. Professor Anthony S. Wierzbicki, Consultant in Metabolic Medicine & Chemical Pathology. Guy's & St Thomas' Hospitals, London, UK. 10.00-10.40Why do we have British guidelines on hypertension, but not hyperlipidaemia? A disservice to people with hyperlipidaemia. Professor Paul Durrington, University of Manchester, Manchester, UK. 10.40-11.00Coffee Session 2Chair Professor Paul Durrington 11.00-11.40An overview and what we learned from Simon Broome registry data? Professor Andrew Neil, Wolfson College, Oxford, UK. 11.40-12.20Genetics of Familial Hypercholesterolaemia. Professor Steve Humphries, University College London, London, UK. 12.20-1300Familial Hypercholesterolaemia cascade testing in Wales; an experience so far. Dr Dev Datta Consultant in Biochemistry and Metabolic Medicine University Hospital Llandough, Wales, UK. 13.00-13.15 Panel Discussion 13.15-14.15Lunch and networking Session 3Chair Dr Mary Seed 14.15-14.50PCSK9: natural history and targeted treatment of GoF Mutations with PCSK9 Monoclonal Antibody and its effect in Homozygous Familial Hypercholestrolaemia. Dr Handrean Soran, Consultant Physician and Endocrinologist, Central Manchester University Hospital NHS Foundation Trust, Manchester, UK. 14.50.15.10Liver transplantation as a therapeutic option in Homozygous Familial Hypercholestrolaemia: Overview of the Literature and a case presentation. Dr Anne-Marie Kelly, Consultant Chemical Pathologist & Hospital Dean, University Hospital of South Manchester NHS Foundation Trust, Manchester, UK. 15.10-15.30Homozygous Familial Hypercholestrolaemia and pregnancy. Sister Ruth Eatough, Cardiovascular Trials Unit, Central Manchester University Hospital NHS Foundation Trust, Manchester, UK. 15.30-15.50A review of paradoxical HDL-C responses to fenofibrate, illustrated by a case report. Dr Jonathan Schofield, Clinical Research Fellow, University of Manchester, Manchester, UK. 16.00Close and feedback Agenda