1. A Wireless Implantable Microsystem for Continuous Blood Glucose Monitoring Currently 200M diabetic people around the world (~ 21M in U.S. in 2002).  Expectation for 2030: 370M Contribution to the death of millions of people.  225,000 people in U.S. in 2002. Monetary cost to the society: billions of dollars.  $130 billion in U.S. in 2002. Currently 200M diabetic people around the world (~ 21M in U.S. in 2002).  Expectation for 2030: 370M Contribution to the death of millions of people.  225,000 people in U.S. in 2002. Monetary cost to the society: billions of dollars.  $130 billion in U.S. in 2002. Continuous blood glucose monitoring can help to significantly (40 to 75%) reduce the symptoms of diabetes.

2. Problems of the Previous Works Using the conventional glucose biosensors.  Requirement for oxygen;  Degradation of the sensor due to the production of hydrogen peroxide (short life-time);  Interference from other chemical species. Using battery for powering the implant  Short life-time;  Hazard of leakage. Large Size  Instability of the sensing environment;  Difficulties in packaging. Using the conventional glucose biosensors.  Requirement for oxygen;  Degradation of the sensor due to the production of hydrogen peroxide (short life-time);  Interference from other chemical species. Using battery for powering the implant  Short life-time;  Hazard of leakage. Large Size  Instability of the sensing environment;  Difficulties in packaging.

3. A New Wireless Implantable Microsystem A new electrochemical glucose sensor. Passive telemetry for data and power transfer between the implant and the external reader. Small size (4  8  1 mm 3 ). A new electrochemical glucose sensor. Passive telemetry for data and power transfer between the implant and the external reader. Small size (4  8  1 mm 3 ).