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Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma Maria Romina Girotti, Filipa Lopes, Natasha Preece,

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Presentation on theme: "Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma Maria Romina Girotti, Filipa Lopes, Natasha Preece,"— Presentation transcript:

1 Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma Maria Romina Girotti, Filipa Lopes, Natasha Preece, Dan Niculescu-Duvaz, Alfonso Zambon, Lawrence Davies, Steven Whittaker, Grazia Saturno, Amaya Viros, Malin Pedersen, Bart M.J.M. Suijkerbuijk, Delphine Menard, Robert McLeary, Louise Johnson, Laura Fish, Sarah Ejiama, Berta Sanchez-Laorden, Juliane Hohloch, Neil Carragher, Kenneth Macleod, Garry Ashton, Anna A. Marusiak, Alberto Fusi, John Brognard, Margaret Frame, Paul Lorigan, Richard Marais, Caroline Springer Cancer Cell Volume 27, Issue 1, Pages 85-96 (January 2015) DOI: 10.1016/j.ccell.2014.11.006 Copyright © 2015 The Authors Terms and Conditions Terms and Conditions

2 Figure 1 Cancer Cell 2015 27, 85-96DOI: (10.1016/j.ccell.2014.11.006) Copyright © 2015 The Authors Terms and Conditions Terms and Conditions

3 Figure 2 Cancer Cell 2015 27, 85-96DOI: (10.1016/j.ccell.2014.11.006) Copyright © 2015 The Authors Terms and Conditions Terms and Conditions

4 Figure 3 Cancer Cell 2015 27, 85-96DOI: (10.1016/j.ccell.2014.11.006) Copyright © 2015 The Authors Terms and Conditions Terms and Conditions

5 Figure 4 Cancer Cell 2015 27, 85-96DOI: (10.1016/j.ccell.2014.11.006) Copyright © 2015 The Authors Terms and Conditions Terms and Conditions

6 Figure 5 Cancer Cell 2015 27, 85-96DOI: (10.1016/j.ccell.2014.11.006) Copyright © 2015 The Authors Terms and Conditions Terms and Conditions

7 Figure 6 Cancer Cell 2015 27, 85-96DOI: (10.1016/j.ccell.2014.11.006) Copyright © 2015 The Authors Terms and Conditions Terms and Conditions

8 Figure 7 Cancer Cell 2015 27, 85-96DOI: (10.1016/j.ccell.2014.11.006) Copyright © 2015 The Authors Terms and Conditions Terms and Conditions

9 Cancer Cell 2015 27, 85-96DOI: (10.1016/j.ccell.2014.11.006) Copyright © 2015 The Authors Terms and Conditions Terms and Conditions

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