1. Management of ST-elevation myocardial infarction according to European and American guidelines

2. comparison of guidlines ESC 2012 and ACCF/AHA terms of class of recommendation level of evidence

3. main common recommendations PCI-capable centre with symptom duration <90 min non-PCI centre <120 min

4. culprit lesion (except cardiogenic shock) radial approach ; thrombus aspiration; DES implantation

5. prasugrel or ticagrelor preferred over clopidogrel

6. During PCI bivalirudin and unfractioned heparin indicated fondaparinux contraindicated

7. dual antiplatelet therapy 12 months BMS 1 month DES 6 months

8. fibrinolysis PCI not possible large infarct PCI in >90 coronary angiography within 3-24 h

9. post-discharge optimising coronary risk factor control smoke cessation rehabilitation programmes medication DAPT 12 month beta-blockers ACE /ARB inhibitors statins: LDL < 70 mg/dl aldosterone inhibitors : left ventricular dysfunction Anticoagulation: left ventricular disfunction, atrial fibrillation

10. Differences