1. Respiratory System Laboratory S.K. Kim

2. #124 Nasal Mucosa (Ep. + Lamina propria) Concha(e) Nasal septum Nasal mucosa respiratory epithelium sero-mucous glands dilated venules and veins Nasal mucosa respiratory epithelium sero-mucous glands dilated venules and veins (hyaline cartilage) Nasal septum Middle concha Inferior concha

3. # 124 #124 Olfactory Mucosa ? (monkey)

4. Slide 124 - Olfactory Epithelium 1.Thicker epithelium compared to respiratory epithelium sustentacular cells* ciliated olfactory cells* basal (stem) cells* NO goblet cells 1.Thicker epithelium compared to respiratory epithelium sustentacular cells* ciliated olfactory cells* basal (stem) cells* NO goblet cells 2.SEROUS (Bowman’s) glands (G) and olfactory nerve fibers (N) in lamina propria *note, can’t tell these cell types apart in routine H&E sections G N N

5. Nasal mucosa Throughout the nasal cavity Respiratory epithelium with goblet cells. Sero- mucous glands in the lamina propria. Dilated venules and veins. Olfactory mucosa Limited to a small area on the roof. Taller epithelium with no goblet cells (Only) serous glands (Bowman’s) in the lamina propria. Dilated venules and veins. Olfactory nerve fibers Bowman’s gland

6. 115N (H&E) Sagital section of the palate palatal and maxillary bone formation by intramembranous ossification Nasal cavity Oral cavity Upper lip Gingiva (gum) Developing tooth Rotate 180 o

7. Nasal cavity, Pharynx and Larynx Oropharynx Laryngopharynx Trachea Esophagus Larynx Nasal cavity (septum) Nasopharynx chonchae Epiglottis Posterior view

8. #125-2 Larynx Thyroid cartilage Laryngeal ventricle Clemente pl. 562 Gray’s p.956

9. Vestibular fold (false vocal fold) (true) Vocal fold #125-2 Larynx

10. Respiratory epithelium Stratified squamous epithelium, non-keratining

11. #126 Trachea Esophagus esophagus trachea Trachealis muscle

12. #127 Trachealis Muscle (smooth)

13. #130-1 Lung 2? 1? Bronchus Pulmonary artery

14. #130-1 Lung Pulmonary artery Close to bronchial trees relatively thin wall (media) elastic laminae relatively wide lumen

15. #130-1 Lung 3? 4? 5?

16. #130-1 Lung 3. Terminal bronchiole 4. Pulmonary artery 5. Alveolar duct

17. #130-1 LungTerminal bronchiole Ciliated and non- ciliated (Clara) cells No goblet cells Prominent sm. M.

18. #132 Lung 7? 6? 8? Terminal bronchiole Respiratory bronchiole P.A. Low cells alveolar pocketing Knobs of sm. muscle (arrows) Low cells alveolar pocketing Knobs of sm. muscle (arrows)

19. Terminal and Respiratory Bronchioles TBr RBr PA AD

20. #129 Lung 9? Alveolar duct 10? alveoli Alveolar sac

21. #130-1 Lung Type I Pneumocyte Type II Pneumocyte (surfactant) Macrophage 10? 11? 12?

22. #130-1 Lung Bronchial cartilage 14? 15? 14? 15? Bronchial vein Bronchial artery Only in the wall of large bronchi. Ordinary arteries with relatively thick media.

23. #129 Lung ? ? ? ? ? ?

24. T. Br. R. Br. A. duct

25. #130-1 Lung Pulmonary vein Away from bronchial trees thin wall 13?

26. #130-2 Lung Pulmonary vein