1. GENETICS OF VIRUSES

2. The Basics Compare the size! Two basic components: – A diverse genome ssDNA dsDNA (Smallpox) ssRNA (Measles) dsRNA – Capsid/Envelope

3. Viral Structure

4. Obligate Intracellular Parasites? Host range varies with virus – Swine flu vs. smallpox Tissue specific – Cold virus to AIDS virus What determines the limits to the host range?

5. Lytic Cycle The “virulent” phage Why are bacteria not extinct?

6. Lysogenic Cycle The “temperate” phage How is the prophage involved?

7. Viral Envelopes Describe the steps: How does Herpes virus differ?

8. Retrovirus HIV

9. Vaccines How do they work? Why can’t viruses be treated with antibiotics? Eradication of viral diseases…how is this possible? – Smallpox (1976)

10. Emerging Viruses Why are some example? Why are they typically RNA viruses? Why do they spread?

11. Plant Viruses

12. Viroids & Prions