1. Bioassay with cultured ganglia

2. Transport of NGF

3. Structure of neurotrophins

4. Structure of neurotrophin receptors

5. Neurotrophin receptor specificity

6. Tyrosine kinase Receptor activation:

7. Tyrosine kinase Receptor activation:

8. Distribution of brain neurotrophins

9. Signaling Pathways:

10. MAP kinase cascade:

11. “Caretaker” neurotrophins during outgrowth

12. Growth factors in the CNS

13. Depolarization and Ca influx enhances growth factor expression

14. Sensory input and growth factor activity throughout development

15. Diffusible factor from mouse sarcoma