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fMRI – “Pluripotentiality” vs. “Degeneracy”
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H.R. Naghavi, L. Nyberg / Consciousness and Cognition 14 (2005) 390–425
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Pluripotentiality (one to many) Structure A Function 2 Function 3 Function 1 State functions? Common processing stage? Or True pluripotentiality? If pluripotentiality – at what level? Lobe? Region? Ansemble? Single neuron?
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Degeneracy (many to one) Structure C Structure B Structure A Function 1 Different normal strategies? Normal anatomical variation?
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Level of description determines Pluripotent\Degenerate Structure: –Multiple regions (network) –Single regions –Neuronal assemplies\populations –Single neurons Function –E.g. “sentence comprehension” vs. [word recognition; working memory; syntactic parsing…”
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Degenerate or not? קריאת מילים “phonology”“orthographic”
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The spatial resolution Intrinsic resolution is determined by the physiology Precision depends on the voxel size + distrotions –Distinguishing two foci is hindered by intersubject variability –Neuronal adaptation technique
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