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How Life Started
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Early Earth
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membrane-bound proto-cells living cells
self-replicating system enclosed in a selectively permeable, protective lipid sphere DNA RNA enzymes and other proteins formation of protein-RNA systems, evolution of DNA lipid spheres spontaneous formation of lipids, carbohydrates, amino acids, proteins, nucleotides under abiotic conditions
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electrodes to vacuum pump spark discharge CH4 NH3 H2O H2 gases water out condenser water in water droplets water containing organic compounds boiling water liquid water in trap
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Figure 14.4(1) Page 224 Do not post to Internet
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Archaebacterial Lineage Ancestors of Eukaryotes Noncyclic pathway of photosynthesis Origin of Prokaryotes Cyclic pathway of photosynthesis Eubacterial Lineage Aerobic respiration 3.8 3.2 2.5 billion years ago
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origin of mitosis, meiosis
ARCHAEBACTERIA Extreme halophiles Methanogens Extreme thermophiles origins of animals EUKARYOTES Animals origins of eukaryotes origins of fungi Fungi Heterotrophic protistans origin of mitosis, meiosis Photosynthetic protistans Photosynthetic protistans endosymbiotic origins of mitochondria Plants origins of plants endosymbiotic origins of chloroplasts EUBACTERIA Oxygen-producing photosynthetic eubacteria Other photosynthetic eubacteria Heterotrophic and chemoautotrophic eubacteria 1.2 billion years ago 900 million years ago 435 million years ago
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cytoplasm with ribosomes
DNA in nucleoid pilus bacterial flagellum outer capsule cell wall plasma membrane
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coccus bacillus spirillum
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Bacterium before DNA replication DNA replication begins DNA replication completed
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cell-wall material deposited
Membrane growth moves DNA molecules apart New membrane and cell-wall material deposited Cytoplasm divided in two Stepped Art
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molecular origin of life
to ancestors of eukaryotes EUBACTERIA ARCHAEBACTERIA spirochetes extreme halophiles methanogens Gram-positive bacteria chlamydias cyanobacteria proteobacteria extreme thermophiles molecular origin of life
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Representative habitat for methanogens
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Representative habitat for extreme thermophiles
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Representative habitat for extreme halophiles
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Figure 14.8d Page 228 Do not post to Internet
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Figure 14.10b Page 229 Do not post to Internet
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Figure 14.11 Page 229 Spirochete that causes Lyme disease Deer ticks
Typical rash Do not post to Internet
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Endospore developing inside a cell of Clostridium tetani
Figure Page 230 spore coat Endospore developing inside a cell of Clostridium tetani Do not post to Internet
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In-text Figure Page 230 Berkeley Pit Lake Do not post to Internet
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Figure 14.13 Page 231 ? branch leading to plants
branch leading to fungi branch leading to animals charophytes green algae Stramenopiles amoeboid protozoans Alveolates brown algae red algae ciliates chrysophytes sporozoans oomycotes ? dinoflagellates “crown” of eukaryotes (rapid divergences) slime molds euglenoids kinetoplastids (e.g., Trypanosoma) parabasalids (e.g., Trichomonas) diplomonads (e.g., Giardia) endosymbiotic origins from prokaryotic ancestors
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Influenza virus A herpes virus Do not post to Internet
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viral protein lipid envelope (derived from host) viral coat (proteins) viral RNA reverse transcriptase enveloped virus (HIV)
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DNA protein coat complex virus sheath base plate tail fiber
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viral RNA protein subunits of coat polyhedral virus helical virus
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Lysis of host cell is induced; infectious particles escape.
Lytic Pathway Tail fibers and other parts are added to coats. Virus particles bind to wall of suitable host. Viral genetic material enters cell cytoplasm. Viral protein molecules are assembled into coats; DNA is packaged inside. Viral DNA directs host machinery to produce viral proteins and viral DNA.
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Viral DNA usually becomes integrated into the bacterial chromosome.
Lysogenic Pathway Viral DNA is excised from chromosome and cell enters lytic pathway. Prior to prokaryotic fission, the chromosome and integrated viral DNA are replicated. After binary fission, each daughter cell will have recombinant DNA.
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* Includes pneumonia, influenza, and whooping cough.
** Includes amoebic dysentery, cryptosporidiosis, and gastroenteritis. 500,000 1 million Bacteria Tetanus 200 million Virus Hepatitis B Viruses Measles 2.6 million 5.6 million Virus (HIV) AIDS 2.5–2.7 million 110 million Sporozoans Malaria 3.1 million 9 million Tuberculosis 1.8 billion Bacteria, viruses, protozoans Diarrhea** 4.7 million 1 billion Bacteria, viruses Acute respiratory infection* Disease Estimated Deaths per Year Estimated New Cases per Year Main Agents Table 14.1 The Eight Deadliest Infectious Diseases Table 14.1 Page 245
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HIV, agent of AIDS Agent of SARS
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