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Choline/NAA Spatial Variation Lars Ewell Radiation Oncology University of Arizona Medical Center 1/25/08 1.

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Presentation on theme: "Choline/NAA Spatial Variation Lars Ewell Radiation Oncology University of Arizona Medical Center 1/25/08 1."— Presentation transcript:

1 Choline/NAA Spatial Variation Lars Ewell Radiation Oncology University of Arizona Medical Center 1/25/08 1

2 Cho/NAA Spatial Variation Cho/NAA has potential for necrosis/disease discrimination Weybright et al., Neuroradiology (2004) 46: 541–549

3 Patient 1: Scanned 3/23/07 S26S46

4 Patient 1, Cho/NAA 3/23/07 Highest ratio near center of disease/radiation. Dark blue not zero, ambiguous, indeterminate spectra.

5 Patient 1, Cho/NAA 5/8/07 Highest ratio moved posterior relative to 3/23/07 spectra. Dark blue not zero, ambiguous, indeterminate spectra.

6 Patient 1: Row and Columns 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15

7 Central Increase going from Inferior to Superior Slice: Columns 6, 7, 8 Peripheral Decrease going from Inferior to Superior Slice: Columns 5, 10, 11

8 Similar behavior for row number 12

9 Closer to lesion, different behavior


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