1. Muscle Tissue Chapter 4 Anatomy and Physiology Mr. Rick Knowles Liberty Senior High School

2. Do you have as many muscle cells as Arnold, girly man?

3. Three Types of Muscle Tissue Skeletal Muscle Tissue Cardiac Muscle Tissue Smooth Muscle Tissue

4. Skeletal Muscle Tissue Long Cells- also known as muscle fibers (+ 1 ft in length). Have many nuclei (multinucleated). Unable to divide, but do have satellite cells (stem cells) that can partially repair damage.

5. Muscle Cell (Fiber) Nuclei Sarcoplasm Sarcolemma

6. Skeletal Muscle Tissue Tissue is Striated- actin and myosin filaments in cells are arranged, have a banded appearance. Contraction stimulated by nerves; voluntary control- Striated Voluntary Muscle.

7. Skeletal Muscle Tissue

9. Motor End Plate

11. Cardiac Muscle Tissue Found only in heart. Is striated. Cells are smaller than skeletal and usually one nucleus. Lack satellite cells-unable to regenerate.

12. Cardiac Muscle Tissue Cells have connections- Intercalated Discs- cell membranes interlocked by CAMs at desmosomes. Also, have gap junctions at these connections. What are their functions?

13. Intercalated Discs Desmosomes- keep cells together during contractions. Gap Junctions- ion movement between cells coordinate contractions.

14. Cardiac Muscle Tissue

15. Do not rely on nerve activity for contraction- have pacemaker cells- involuntary contraction (ANS). Also called Striated Involuntary Muscle

16. So if cardiac muscle can’t regenerate, what happens after a heart attack? Can we grow new cardiac cells for the heart? Movie- Scientific American: Never Say Die

17. Smooth Muscle Tissue Line blood vessels, hollow organs (bladder), respiratory and digestive tracts. Cells are small, spindle- shaped with single nucleus. Can divide and regenerate.

18. Smooth Muscle Tissue No striations. Contraction part of the ANS, involuntary.Ex. Peristolsis Do have gap junctions- coordinate contractions. Nonstriated Involuntary Muscle

19. Smooth Muscle Tissue