1. Worldwide Laboratory Based Influenza Surveillance Linda C. Canas Brooks AFB San Antonio, TX

2. ANNUAL MESSAGE SELECTED ISOLATES Epidemiology and Laboratory personnel provide: -Program Oversight -Annual Guidance Letter USAF Surgeon General’s Office (EA) Sentinel Sites Brooks AFB Virology Laboratory -Isolation and Identification Disease Surveillance, Results Analysis CDCSubmitting Sites Vaccine Decisions SUPPLIES DoD Global Influenza Surveillance................................IN ACTION COLLECT/SHIP SPECIMENS USAF Surgeon General’s Office, DoD GEIS REPORTS INPUT Improvements PATIENT RESULTS

3. 2000-2001 Sentinel Sites

4. All Sites 1999 - 2000 2000 - 2001

5. North America 1999 - 20002000 - 2001

6. Pacific Rim Japan Korea Singapore Guam Hawaii 1999 - 20002000 - 2001

7. Europe UK Germany Turkey Italy Spain 1999 - 2000 2000 - 2001

8. South America Argentina Ecuador Peru

9. Nepal and Thailand

10. Influenza Subtypes by Region 2000-2001 Season

11. B/Beijing-like Subtype by Region

12. H1N1 Subtype by Region

13. H3N2 Subtype by Region

14. Influenza A Subtypes by Season

15. Flu B H1N1 H3N2 % Nucleotide Homology of HA1 to Reference Strains

16. Summary for 1999-2001 99-00 Influenza Season99-00 Influenza Season –Predominately H3N2 worldwide and U.S.A. –Panama 2007 strain included in vaccine. –Early detection of Peru strains incited the NC/20/99 vaccine component. –Molecular and immunological descriptions of these Peru strains being prepared for publication with CDC. 00-01 Influenza Season00-01 Influenza Season –Predominately H1N1 and B. –Nepal isolates currently being analyzed.